加拿大老龄化纵向研究中心理健康和人格特质对慢性咳嗽发病率的影响。
Impact of mental health and personality traits on the incidence of chronic cough in the Canadian Longitudinal Study on Aging.
作者信息
Satia Imran, Mayhew Alexandra J, Sohel Nazmul, Kurmi Om, Killian Kieran J, O'Byrne Paul M, Raina Parminder
机构信息
Dept of Medicine, McMaster University, Hamilton, ON, Canada.
Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamilton, ON, Canada.
出版信息
ERJ Open Res. 2022 May 30;8(2). doi: 10.1183/23120541.00119-2022. eCollection 2022 Apr.
BACKGROUND
Chronic cough is a common troublesome condition, but risk factors for developing chronic cough are poorly understood. The aim of this study was to understand the relationship between mental health disorders, personality traits and chronic cough.
METHODS
The Canadian Longitudinal Study on Aging is a prospective, nationally generalisable, random sample of adults aged 45-85 years at baseline recruited between 2011 and 2015, and followed-up 3 years later. Chronic cough was defined as a daily cough over the last 12 months. Incident chronic cough was defined as those participants who reported new-onset chronic cough between baseline and follow-up 1. Current depressive symptoms and psychological distress were assessed using the Center for Epidemiologic Study Short Depression Scale (CESD-10) and Kessler Psychological Distress Scale (K-10), respectively. The "Big Five" personality traits were assessed using the Ten-Item Personality Inventory. Relative risks are reported using a multivariate mutually adjusted model.
RESULTS
At follow-up 1, 2506 participants (11.1%) reported new-onset chronic cough during the ∼3-year interval. Depressive symptoms (CESD-10 ≥10: relative risk 1.22 (95% CI 1.03-1.44)) and psychological distress (K-10 ≥22: relative risk 1.20 (95% CI 1.07-1.36)) at baseline were both independent predictors of a higher risk of incident chronic cough. Prevalent and incident chronic cough were also independently associated with an increased risk of developing depressive symptoms and psychological distress. Personality traits did not influence the development of chronic cough but did increase the risk of depressive symptoms and psychological distress.
CONCLUSIONS
This study shows that there is a bidirectional relationship between chronic cough, and depressive symptoms and psychological distress, and personality traits do not independently influence the development of chronic cough.
背景
慢性咳嗽是一种常见的困扰性疾病，但对其发病的危险因素了解甚少。本研究旨在了解心理健康障碍、人格特质与慢性咳嗽之间的关系。
方法
加拿大老龄化纵向研究是一项前瞻性、具有全国代表性的随机抽样研究，研究对象为2011年至2015年基线时年龄在45 - 85岁的成年人，并在3年后进行随访。慢性咳嗽定义为过去12个月内每天咳嗽。新发慢性咳嗽定义为在基线和随访1期间报告新发慢性咳嗽的参与者。分别使用流行病学研究中心短抑郁量表（CESD - 10）和凯斯勒心理困扰量表（K - 10）评估当前的抑郁症状和心理困扰。使用十项人格量表评估“大五”人格特质。使用多变量相互调整模型报告相对风险。
结果
在随访1时，2506名参与者（11.1%）报告在约3年的时间间隔内出现新发慢性咳嗽。基线时的抑郁症状（CESD - 10≥10：相对风险1.22（95%可信区间1.03 - 1.44））和心理困扰（K - 10≥22：相对风险1.20（95%可信区间1.07 - 1.36））均是新发慢性咳嗽风险较高的独立预测因素。现患和新发慢性咳嗽也分别与抑郁症状和心理困扰发生风险增加独立相关。人格特质不影响慢性咳嗽的发生，但会增加抑郁症状和心理困扰的风险。
结论
本研究表明慢性咳嗽与抑郁症状和心理困扰之间存在双向关系，人格特质不独立影响慢性咳嗽的发生。
Zotero 插件