Advanced Studies and Research Center in Dentistry "Dr Keisaburo Miyata" of Faculty of Dentistry, Autonomous University of the State of Mexico, Toluca, Mexico.
Academic Area of Dentistry of Health Sciences Institute, Autonomous University of Hidalgo State, Pachuca, México.
Cleft Palate Craniofac J. 2023 Nov;60(11):1353-1358. doi: 10.1177/10556656221106881. Epub 2022 Jun 6.
To describe trends in cases and prevalence at birth rates of cleft lip and/or palate (CL/P) in Mexico between 2003 and 2019.
Ecological study.
Multiple data sources systematically collected into a national epidemiological surveillance data warehouse.
National Live Birth Information System.
MAIN OUTCOME MEASURE(S): Both cases and prevalence at birth rates of CL/P in Mexico within a 17-year period were used as dependent variables.
At the national level there were 23 184 new cases of CL/P (average of 1364 per year) in the 32 states of Mexico, with an average prevalence at birth rate of 0.53 per 1000 live births. The states with the highest prevalence at birth rates of CL/P during the period were Hidalgo (1.59) and Jalisco (1.32), while the states with the lowest rates were Nayarit (0.22) and Durango (0.29). A slight decrease in both cases (z = -2.41, = .016) and prevalence at birth rates (z = -2.58, = .010) of CL/P was observed at the national level. States such as Durango, Puebla, Chiapas, Guerrero, Oaxaca, Mexico City, State of Mexico, Coahuila and Jalisco showed a clear downward trend ( < .05) in their prevalence at birth of CL/P between 2003 and 2019, while in Hidalgo its trend was upward ( = .05). Significant differences by sex and region were observed ( < .05).
Some states consistently had the highest or lowest prevalence of CL/P. Decreasing trends in the overall prevalence at birth rates were observed. More detailed, epidemiological studies are necessary to adequately characterize CL/P in the Mexican population.
描述 2003 年至 2019 年期间墨西哥唇腭裂（CL/P）病例和患病率的变化趋势。
生态研究。
多个数据源系统地收集到一个国家流行病学监测数据仓库中。
全国活产信息系统。
17 年间墨西哥 CL/P 的病例数和患病率作为因变量。
在全国范围内，墨西哥 32 个州共有 23184 例新的 CL/P 病例（平均每年 1364 例），出生时的平均患病率为每 1000 例活产 0.53 例。在此期间，CL/P 出生时患病率最高的州是伊达尔戈州（1.59）和哈利斯科州（1.32），而患病率最低的州是纳亚里特州（0.22）和杜兰戈州（0.29）。全国范围内，CL/P 的病例数（z=-2.41，=0.016）和患病率（z=-2.58，=0.010）均略有下降。杜兰戈州、普埃布拉州、恰帕斯州、格雷罗州、瓦哈卡州、墨西哥城、墨西哥州、科阿韦拉州和哈利斯科州等州的 CL/P 出生时患病率呈明显下降趋势（ < 0.05），而伊达尔戈州的趋势呈上升趋势（ = 0.05）。性别和地区之间存在显著差异（ < 0.05）。
一些州的 CL/P 患病率一直较高或较低。总体出生时患病率呈下降趋势。需要更详细的流行病学研究来充分描述墨西哥人口中的 CL/P。
