正常黏膜活检能否预测接受根治性放疗的膀胱移行细胞癌患者的预后？
Do normal mucosal biopsies predict prognosis in patients with transitional cell carcinoma of bladder treated by radical radiotherapy?
作者信息
Quilty P M, Hargreave T B, Smith G, Duncan W
出版信息
Br J Urol. 1987 Mar;59(3):242-7. doi: 10.1111/j.1464-410x.1987.tb04615.x.
Abstract
A biopsy of normal-looking mucosa showed mucosal abnormalities in 48.9% of patients with transitional cell carcinoma of the bladder. The presence of dysplasia or carcinoma in situ was significantly associated with grade but not with tumour category. In 100 patients who completed a course of radical megavoltage X-ray therapy, the result of mucosal biopsy gave no significant prognostic information about tumour regression, durable local control, survival or the risk of subsequent metastases.
摘要
对外观正常的黏膜进行活检显示，48.9%的膀胱移行细胞癌患者存在黏膜异常。发育异常或原位癌的存在与肿瘤分级显著相关，但与肿瘤类别无关。在100例完成根治性兆伏级X线治疗疗程的患者中，黏膜活检结果对于肿瘤消退、持久局部控制、生存或后续转移风险并无显著的预后信息。
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