Cancer Prevention Fellowship Program, Implementation Science, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, 20850, USA.
Prevention Research Center, Brown School at Washington University in St. Louis, St. Louis, MO, USA.
Syst Rev. 2022 Jun 8;11(1):117. doi: 10.1186/s13643-022-01995-4.
Improving the delivery, uptake, and implementation of cancer screening to meet evidence-based recommendations is needed to reduce persistent cancer health disparities in the USA. Current national public health targets emphasize the role of social determinants of health (SDOH) on cancer screening. However, there remains a need to explicate these linkages, toward the goal of identifying and implementing effective interventions that target and address SDOH to reduce inequities in cancer screening.
We will conduct a systematic review of English language peer-reviewed original research articles published between 2010 and 2021 that describe observational (qualitative and quantitative) and intervention studies conducted in the USA. In alignment with Healthy People 2030, we will include studies of breast, cervical, colorectal, and/or lung cancer screening. Guided by multiple SDOH frameworks, we will broadly define SDOH by five domain areas: economic stability, education access and quality, healthcare access and quality, neighborhood and built environment, and social and community context. Following systematic literature searches in five databases (Ovid MEDLINE, Embase, CINAHL, Web of Science, Cochrane Library) and piloting of screening procedures, reviewers will independently screen titles/abstracts for potential relevance. Reviewer pairs will then screen full text articles for eligibility criteria. We will extract data items from included articles, including study characteristics, cancer screening intervention information, and coding of SDOH constructs. We will assess study quality using the Mixed Methods Appraisal Tool and synthesize our findings using narrative, descriptive statistics, tables, and figures. Our approach will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) recommendations.
By completing this systematic review, we will summarize recent literature on SDOH and cancer screening, identify research gaps for inclusion of SDOH, and propose future opportunities for advancing equity in cancer screening by integrating SDOH as part of the implementation context to promote uptake, sustainability, and scale-up in the implementation of screening guidelines.
PROSPERO CRD42021276582 .
为了减少美国持续存在的癌症健康差异，需要改善癌症筛查的提供、接受和实施，以符合循证建议。当前的国家公共卫生目标强调了社会决定因素（SDOH）对癌症筛查的作用。然而，仍有必要详细说明这些联系，以确定和实施有效的干预措施，针对和解决 SDOH，从而减少癌症筛查中的不平等。
我们将对 2010 年至 2021 年间发表的英语同行评审原始研究文章进行系统回顾，这些文章描述了在美国进行的观察性（定性和定量）和干预研究。根据《健康人民 2030》，我们将包括乳腺癌、宫颈癌、结直肠癌和/或肺癌筛查的研究。根据多个 SDOH 框架，我们将通过五个领域广泛定义 SDOH：经济稳定性、教育机会和质量、医疗保健机会和质量、邻里和建筑环境以及社会和社区环境。在对五个数据库（Ovid MEDLINE、Embase、CINAHL、Web of Science、Cochrane Library）进行系统文献检索和筛选程序试点后，审查员将独立筛选标题/摘要以确定其相关性。审查员对将然后筛选全文文章以确定是否符合入选标准。我们将从纳入的文章中提取数据项，包括研究特征、癌症筛查干预信息和 SDOH 结构的编码。我们将使用混合方法评估工具评估研究质量，并使用叙述、描述性统计、表格和图形综合我们的发现。我们的方法将遵循系统评价和荟萃分析的首选报告项目（PRISMA）建议。
通过完成这项系统回顾，我们将总结最近关于 SDOH 和癌症筛查的文献，确定纳入 SDOH 的研究空白，并提出通过将 SDOH 作为实施背景的一部分纳入未来机会，以促进筛查指南的接受、可持续性和扩大规模，从而推进癌症筛查中的公平性。
PROSPERO CRD42021276582。
