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种族和民族与急性非 ST 段抬高型心肌梗死管理的关联。

Association of Race and Ethnicity on the Management of Acute Non-ST-Segment Elevation Myocardial Infarction.

机构信息

Department of Medicine University of Pittsburgh Medical Center Pittsburgh Pennsylvania.

Division of Cardiology UPMC Heart and Vascular Institute, University of Pittsburgh Pittsburgh Pennsylvania.

出版信息

J Am Heart Assoc. 2022 Jun 21;11(12):e025758. doi: 10.1161/JAHA.121.025758. Epub 2022 Jun 14.

Abstract

Background Prior studies have reported disparities by race in the management of acute myocardial infarction (MI), with many studies having limited covariates or now dated. We examined racial and ethnic differences in the management of MI, specifically non-ST-segment-elevation MI (NSTEMI), in a large, socially diverse cohort of insured patients. We hypothesized that the racial and ethnic disparities in the receipt of coronary angiography or percutaneous coronary intervention would persist in contemporary data. Methods and Results We identified individuals presenting with incident, type I NSTEMI from 2017 to 2019 captured by a health claims database. Race and ethnicity were categorized by the database as Asian, Black, Hispanic, or White. Covariates included demographics (age, sex, race, and ethnicity); Elixhauser variables, including cardiovascular risk factors and other comorbid conditions; and social factors of estimated annual household income and educational attainment. We examined rates of coronary angiography and percutaneous coronary intervention by race and ethnicity and income categories and in multivariable-adjusted models. We identified 87 094 individuals (age 73.8±11.6 years; 55.6% male; 2.6% Asian, 13.4% Black, 11.2% Hispanic, 72.7% White) with incident NSTEMI events from 2017 to 2019. Individuals of Black race were less likely to undergo coronary angiography (odds ratio [OR], 0.93; [95% CI, 0.89-0.98]) and percutaneous coronary intervention (OR, 0.86; [95% CI, 0.81-0.90]) than those of White race. Hispanic individuals were less likely (OR, 0.88; [95% CI, 0.84-0.93]) to undergo coronary angiography and percutaneous coronary intervention (OR, 0.85; [95% CI, 0.81-0.89]) than those of White race. Higher annual household income attenuated differences in the receipt of coronary angiography across all racial and ethnic groups. Conclusions We identified significant racial and ethnic differences in the management of individuals presenting with NSTEMI that were marginally attenuated by higher household income. Our findings suggest continued evidence of health inequities in contemporary NSTEMI treatment.

摘要

背景 先前的研究报告称,在急性心肌梗死(MI)的治疗方面,不同种族之间存在差异,许多研究的协变量有限或已经过时。我们在一个大型、社会多样化的参保人群中,研究了 MI,特别是非 ST 段抬高型 MI(NSTEMI)的管理方面的种族和民族差异。我们假设,在当代数据中,接受冠状动脉造影或经皮冠状动脉介入治疗的种族和民族差异仍然存在。

方法和结果 我们从健康索赔数据库中确定了 2017 年至 2019 年期间因 I 型 NSTEMI 而就诊的个体。种族和民族由数据库分类为亚洲人、黑人、西班牙裔或白人。协变量包括人口统计学特征(年龄、性别、种族和民族);Elixhauser 变量,包括心血管危险因素和其他合并症;以及估计的年收入和教育程度等社会因素。我们按种族、民族和收入类别以及多变量调整模型检查了冠状动脉造影和经皮冠状动脉介入治疗的比例。我们确定了 87094 名(年龄 73.8±11.6 岁;男性 55.6%;2.6%亚洲人、13.4%黑人、11.2%西班牙裔、72.7%白人)在 2017 年至 2019 年期间患有 I 型 NSTEMI 的个体。与白人相比,黑人种族的个体接受冠状动脉造影的可能性较小(比值比[OR],0.93;[95%可信区间,0.89-0.98])和经皮冠状动脉介入治疗(OR,0.86;[95%可信区间,0.81-0.90])。与白人相比,西班牙裔个体接受冠状动脉造影(OR,0.88;[95%可信区间,0.84-0.93])和经皮冠状动脉介入治疗(OR,0.85;[95%可信区间,0.81-0.89])的可能性较小。较高的年收入减轻了所有种族和民族接受冠状动脉造影的差异。

结论 我们发现,在 NSTEMI 患者的管理方面,不同种族之间存在显著差异,而较高的家庭收入则略微减轻了这些差异。我们的研究结果表明,当代 NSTEMI 治疗中仍存在健康不平等的证据。

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