Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.
Biomedical Engineering Unit, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Chem Rec. 2022 Sep;22(9):e202200058. doi: 10.1002/tcr.202200058. Epub 2022 Jun 14.
The scientific field is observing a gradual shift from monolayer cultures to three-dimensional (3D) models, as they give a more relevant data in pre-clinical stages. This review summarizes the major techniques and materials used to develop 3D platforms, especially for cancer. It also discusses the challenges and some unresolved issues of the field and highlights some techniques that have made it to the market.
科学领域正逐渐从单层培养转向三维（3D）模型，因为它们在临床前阶段提供了更相关的数据。本文综述了用于开发 3D 平台的主要技术和材料，特别是用于癌症的 3D 平台。本文还讨论了该领域的挑战和一些未解决的问题，并强调了一些已经推向市场的技术。
