Çelik Mine, Yayık Ahmet Murat, Kerget Buğra, Kerget Ferhan, Doymuş Ömer, Aksakal Alperen, Özmen Sevilay, Aslan Mehtap Hülya, Uzun Yakup
Department of Anesthesiology and Reanimation, Atatürk University Faculty of Medicine, Erzurum, Turkey; Clinical Research, Development and Design Application and Research Center, Atatürk University Faculty of Medicine, Erzurum, Turkey.
Department of Pulmonary Diseases, Atatürk University Faculty of Medicine, Erzurum, Turkey.
Eurasian J Med. 2022 Jun;54(2):150-156. doi: 10.5152/eurasianjmed.2022.21048.
Coronavirus 2019 disease presents in a spectrum that can range from mild viral infection to pneu- monia. Common symptoms of coronavirus disease 2019 pneumonia include cough, sputum, and shortness of breath. High-frequency chest wall oscillation is a pulmonary rehabilitation method used for the recovery of pulmonary functions and removal of secretions in the lungs. The aim of the study was to evaluate the efficacy of high-frequency chest wall oscillation on patients with coronavirus disease 2019 pneumonia.
In this study, 100 patients, between 18 and 70 years old, with a positive polymerase chain reaction result for coronavirus disease 2019, were included. Standard medical treatment was applied to all patients. In group rehabilitation, high-frequency chest wall oscillation treatment was applied twice a day for 20 minutes for 5 days. No additional intervention was made to the control group. Pulmonary function tests and oxygenation were evaluated on the first and fifth days. Patients' high-flow oxygen, non-invasive mechani- cal ventilation, and invasive mechanical ventilation needs were evaluated and recorded.
Compared with the control group, the forced expiratory volume in 1 second, forced vital capacity, and peak expiratory flow rates were statistically higher in the rehabilitation group on the fifth day (P < .05). On evaluating the oxygenation of patients, the fifth day to first-day oxygen saturation difference was signifi- cantly higher in rehabilitation group than in control group (P < .05). Furthermore, the number of patients who needed non-invasive mechanical ventilation was lower in the rehabilitation group (P < .05).
This study demonstrated that pulmonary rehabilitation applied with the high-frequency chest wall oscillation device in patients with coronavirus disease 2019 in the early period contributed to the improvement of oxygenation by providing significant improvement as observed in the pulmonary function tests of the patients.
2019冠状病毒病的表现范围从轻度病毒感染到肺炎不等。2019冠状病毒病肺炎的常见症状包括咳嗽、咳痰和呼吸急促。高频胸壁振荡是一种用于恢复肺功能和清除肺部分泌物的肺康复方法。本研究的目的是评估高频胸壁振荡对2019冠状病毒病肺炎患者的疗效。
本研究纳入了100例年龄在18至70岁之间、2019冠状病毒病聚合酶链反应结果呈阳性的患者。所有患者均接受标准药物治疗。康复组每天进行2次高频胸壁振荡治疗，每次20分钟，共5天。对照组不进行额外干预。在第1天和第5天评估肺功能测试和氧合情况。评估并记录患者对高流量氧气、无创机械通气和有创机械通气的需求。
与对照组相比，康复组在第5天的第1秒用力呼气量、用力肺活量和呼气峰值流速在统计学上更高（P < 0.05）。在评估患者的氧合情况时，康复组第5天与第1天的血氧饱和度差值明显高于对照组（P < 0.05）。此外，康复组需要无创机械通气的患者数量较少（P < 0.05）。
本研究表明，在2019冠状病毒病患者早期使用高频胸壁振荡装置进行肺康复，有助于改善氧合，这在患者的肺功能测试中得到了显著体现。
