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Biosynthesis of the antibiotic actinorhodin. Analysis of blocked mutants of Streptomyces coelicolor.

作者信息

Cole S P, Rudd B A, Hopwood D A, Chang C J, Floss H G

出版信息

J Antibiot (Tokyo). 1987 Mar;40(3):340-7. doi: 10.7164/antibiotics.40.340.

Abstract

From two types of class V act mutants of Streptomyces coelicolor two monomeric precursors of actinorhodin have been isolated and their structures determined. One is the known antibiotic kalafungin and the other a new compound. Their relationship to actinorhodin biosynthesis is discussed.

摘要

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