Devadiga Darshana, Shetty Pushparaj, Hegde Mithra N, Reddy Upasana
Department of Conservative Dentistry and Endodontics, A.B. Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangalore, Karnataka, India.
Department of Oral and Maxillofacial Pathology, A.B. Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangalore, Karnataka, India.
J Conserv Dent. 2022 Jan-Feb;25(1):93-97. doi: 10.4103/jcd.jcd_583_21. Epub 2022 May 2.
With the increasing prevalence of erosive tooth wear affecting both adults and children; designing optimum protocols of management in a noninvasive manner is gaining precedence.
Comparative evaluation of topically applied calcium phosphate-based agents casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and beta tricalcium phosphate (β-TCP) on the surface of eroded dentin.
Dentin blocks from human third molars in four groups were subjected to the surface treatment: (G1) sound dentin (G2) demineralized dentin (G3) CPP-ACP (G4) β-TCP. All the samples except control (G1) were immersed in an acidic solution incubated at 37°C for 96 h. The samples in G3 and G4 were topically treated with CPP-ACP and β-TCP for 4 min twice daily for 14 days; followed by pH-cycling for 21 days. Surface hardness testing and surface morphology were observed using the scanning electron microscopy. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) software with Kruskal-Wallis test and test.
Dentin treated with both CPP-ACP (37.25) and β-TCP (32.05) recorded significantly higher VHN than demineralized (G2-23.51) but lower compared to sound control (G1-57.06).
The topical application of CPP-ACP and β-TCP agents shows definite potential in promoting the hardening of demineralized dentin surface.
随着侵蚀性牙齿磨损在成人和儿童中患病率的不断上升，以非侵入性方式设计最佳治疗方案变得愈发重要。
比较局部应用磷酸钙基制剂酪蛋白磷酸肽 - 无定形磷酸钙（CPP - ACP）和β - 磷酸三钙（β - TCP）对侵蚀性牙本质表面的影响。
将四组人第三磨牙的牙本质块进行表面处理：（G1）健康牙本质；（G2）脱矿牙本质；（G3）CPP - ACP处理组；（G4）β - TCP处理组。除对照组（G1）外，所有样本均浸泡在37°C的酸性溶液中96小时。G3和G4组的样本每天两次局部应用CPP - ACP和β - TCP，每次4分钟，持续14天；随后进行21天的pH循环。使用扫描电子显微镜观察表面硬度测试和表面形态。数据采用社会科学统计软件包（SPSS）进行分析，采用Kruskal - Wallis检验和检验。
经CPP - ACP（37.25）和β - TCP（32.05）处理的牙本质的维氏硬度值（VHN）显著高于脱矿组（G2 - 23.51），但低于健康对照组（G1 - 57.06）。
局部应用CPP - ACP和β - TCP制剂在促进脱矿牙本质表面硬化方面显示出一定潜力。
