Understanding the Dynamics of Blast Resistance in Rice- Interactions.

Rice is a global food grain crop for more than one-third of the human population and a source for food and nutritional security. Rice production is subjected to various stresses; blast disease caused by is one of the major biotic stresses that has the potential to destroy total crop under severe conditions. In the present review, we discuss the importance of rice and blast disease in the present and future global context, genomics and molecular biology of blast pathogen and rice, and the molecular interplay between rice- interaction governed by different gene interaction models. We also elaborated in detail on effector and genes, and the role of noncoding RNAs in disease development. Further, rice blast resistance QTLs; resistance () genes; and alleles identified, cloned, and characterized are discussed. We also discuss the utilization of QTLs and genes for blast resistance through conventional breeding and transgenic approaches. Finally, we review the demonstrated examples and potential applications of the latest genome-editing tools in understanding and managing blast disease in rice.