Institute of Research on Chemical and Biological Analysis (IAQBUS), Universidade de Santiago de Compostela, Constantino Candeira SN, 15782 Santiago de Compostela, Spain.
INTECMAR-Technological Institute for the Monitoring of the Marine Environment in Galicia, Peirao de Vilaxoán S/N, 36611 Vilagarcía de Arousa, Spain.
Molecules. 2022 Jun 18;27(12):3915. doi: 10.3390/molecules27123915.
Contaminants of emerging concern (CECs) are compounds of diverse origins that have not been deeply studied in the past which are now accruing growing environmental interest. The NOR-Water project aimed to identify the main CECs and their sources in the water environment of Northern Portugal-Galicia (located in northwest Spain) transnational region. To achieve these goals, a suspect screening analytical methodology based on the use of liquid chromatography coupled to high resolution mass spectrometry (LC-HRMS) was applied to 29 sampling sites in two campaigns. These sampling sites included river and sea water, as well as treated wastewater. The screening was driven by a library of over 3500 compounds, which included 604 compounds prioritized from different relevant lists on the basis of the persistency, mobility, and toxicity criteria. Thus, a total of 343 chemicals could be tentatively identified in the analyzed samples. This list of 343 identified chemicals was submitted to the classification workflow used for prioritization and resulted in 153 chemicals tentatively classified as persistent, mobile, and toxic (PMT) and 23 as very persistent and very mobile (vMvP), pinpointing the relevance of these types of chemicals in the aqueous environment. Pharmaceuticals, such as the antidepressant venlafaxine or the antipsychotic sulpiride, and industrial chemicals, especially high production volume chemicals (HPVC) such as ε-caprolactam, were the groups of compounds that were detected at the highest frequencies.
新兴关注污染物（CECs）是指过去未被深入研究但现在日益受到环境关注的各种来源的化合物。NOR-Water 项目旨在确定葡萄牙-加利西亚（位于西班牙西北部）跨国地区北部水环境中的主要 CECs 及其来源。为了实现这些目标，采用了一种基于液相色谱与高分辨率质谱联用（LC-HRMS）的可疑筛选分析方法，对两批 29 个采样点进行了分析。这些采样点包括河水、海水和处理后的废水。筛选工作由一个包含 3500 多种化合物的库驱动，其中包括根据持久性、迁移性和毒性标准从不同相关清单中优先选择的 604 种化合物。因此，在分析的样品中可以暂定识别出 343 种化学物质。这 343 种已识别化学物质的清单提交给了用于优先级划分的分类工作流程，其中 153 种化学物质被暂定归类为持久性、迁移性和毒性（PMT），23 种化学物质被归类为非常持久性和非常迁移性（vMvP），这突出了这些类型的化学物质在水环境中的重要性。药物，如抗抑郁药文拉法辛或抗精神病药舒必利，以及工业化学品，特别是高产量化学品（HPVC），如己内酰胺，是检测到的频率最高的化合物组。
