Dahanayake Madushani H, Athukorala Sandya S, Jayasundera A C A
Department of Chemistry, Faculty of Science, University of Peradeniya Sri Lanka
National Institute of Fundamental Studies Hanthana Kandy Sri Lanka.
RSC Adv. 2022 Jun 1;12(26):16369-16385. doi: 10.1039/d2ra01567f.
COVID-19 persists as the most challenging pandemic of the 21 century with a high rate of transmission. The main pathway of SARS-CoV-2 transmission is aerosol-mediated infection transfer through virus-laden droplets that are expelled by infected people, whereas indirect transmission occurs when contact is made with a contaminated surface. This mini review delivers an overview of the current state of knowledge, research directions, and applications by examining the most recent developments in antiviral surface coatings and filters and analyzing their efficiencies. Reusable masks and other personal protective devices with antiviral properties and self-decontamination could be valuable tools in the fight against viral spread. Moreover, antiviral surface coatings that repel pathogens by preventing adhesion or neutralize pathogens with self-sanitizing ability are assumed to be the most desirable for terminating indirect transmission of viruses. Although many nanomaterials have shown high antiviral capacities, additional research is unquestionably required to develop next-generation antiviral agents with unique characteristics to face future viral outbreaks.
新冠疫情仍然是21世纪最具挑战性的大流行病,传播率很高。严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的主要传播途径是通过感染者呼出的载有病毒的飞沫进行气溶胶介导的感染传播,而当接触受污染表面时则会发生间接传播。本综述通过研究抗病毒表面涂层和过滤器的最新进展并分析其效率,概述了当前的知识状态、研究方向和应用。具有抗病毒特性和自我净化功能的可重复使用口罩及其他个人防护设备可能是抗击病毒传播的宝贵工具。此外,通过防止病原体粘附来排斥病原体或具有自我消毒能力以中和病原体的抗病毒表面涂层被认为是终止病毒间接传播的最理想选择。尽管许多纳米材料已显示出高抗病毒能力,但无疑还需要更多研究来开发具有独特特性的下一代抗病毒剂,以应对未来的病毒爆发。