Lenka Abhishek, Pandey Sanjay
MedStar Georgetown University Hospital (AL), Washington, DC; and G.B. Pant Institute of Postgraduate Medical Education and Research (SP), New Delhi, India.
Neurol Clin Pract. 2022 Apr;12(2):183-186. doi: 10.1212/CPJ.0000000000001145.
To highlight five new things in the research and clinical aspects of essential tremor (ET).
The introduction of a new definition of ET and a new category "ET plus" were the major themes of the recent consensus statement. This new change demands a change in the approach to the clinical diagnosis of ET and related diseases. From the pathogenesis standpoint, the cerebellar neurodegenerative model seems to have abundant evidence in its favor compared with the olivary model, which has largely fallen out of favor. From the standpoint of therapeutics, magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy has enriched the therapeutic armamentarium.
There has been considerable progress in the field of ET. We discuss five new things in this article, which include (1) new definition, (2) ET plus, (3) approach to the diagnosis of ET, (4) cerebellar degeneration, and (5) MRgFUS thalamotomy.
强调特发性震颤（ET）研究和临床方面的五个新进展。
ET新定义的引入以及“ET加”这一新类别是近期共识声明的主要主题。这一新变化要求改变ET及相关疾病的临床诊断方法。从发病机制角度来看，与已基本失宠的橄榄核模型相比，小脑神经退行性模型似乎有大量证据支持。从治疗角度而言，磁共振引导聚焦超声（MRgFUS）丘脑切开术丰富了治疗手段。
ET领域取得了显著进展。我们在本文中讨论了五个新进展，包括（1）新定义，（2）ET加，（3）ET诊断方法，（4）小脑变性，以及（5）MRgFUS丘脑切开术。
