Liddle P F
Psychol Med. 1987 Feb;17(1):49-57. doi: 10.1017/s0033291700012976.
In a sample of chronic schizophrenic patients, a group of symptoms which included poverty of speech and lack of spontaneous movement was found to be associated with poor performance in tests of conceptual thinking, object naming and long-term memory, and also with cortical neurological signs. A second group of symptoms which included formal thought disorder and inappropriate affect was associated with poor performance in tests of concentration, immediate recall and word learning, and with cortical neurological signs. The findings suggest that these two syndromes are associated with dysfunction at two different sites within the frontal lobes. A third group of symptoms, comprising various delusions and hallucinations, was associated with poor figure-ground perception, and might reflect temporal lobe dysfunction.
在一组慢性精神分裂症患者中，发现一组包括言语贫乏和自发运动缺乏的症状与概念思维、物体命名及长期记忆测试中的不佳表现相关，也与皮质神经学体征相关。第二组症状包括形式思维障碍和情感不恰当，与注意力、即刻回忆及单词学习测试中的不佳表现以及皮质神经学体征相关。这些发现表明，这两种综合征与额叶内两个不同部位的功能障碍相关。第三组症状包括各种妄想和幻觉，与图形-背景感知不佳相关，可能反映颞叶功能障碍。
