阿尔法折叠的突破概述。
An Overview of Alphafold's Breakthrough.
作者信息
Marcu Ştefan-Bogdan, Tăbîrcă Sabin, Tangney Mark
机构信息
Department of Computer Science, University College Cork, Cork, Ireland.
Department of Informatics, Faculty of Informatics and Mathematics, Transilvania University, Brasov, Romania.
出版信息
Front Artif Intell. 2022 Jun 9;5:875587. doi: 10.3389/frai.2022.875587. eCollection 2022.
This paper presents a short summary of the protein folding problem, what it is and why it is significant. Introduces the CASP competition and how accuracy is measured. Looks at different approaches for solving the problem followed by a review of the current breakthroughs in the field introduced by AlphaFold 1 and AlphaFold 2.
本文简要概述了蛋白质折叠问题，包括其是什么以及为何重要。介绍了蛋白质结构预测关键评估（CASP）竞赛以及准确性的衡量方式。探讨了解决该问题的不同方法，随后回顾了由AlphaFold 1和AlphaFold 2带来的该领域当前的突破。
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