School of Engineering, RMIT University, Melbourne, Victoria, 3000, Australia.
School of Physics and Astronomy, Monash University, Clayton, Victoria 3800, Australia.
Mater Horiz. 2022 Aug 30;9(9):2288-2324. doi: 10.1039/d2mh00263a.
Metal oxides modified with dopants and defects are an emerging class of novel materials supporting the localized surface plasmon resonance across a wide range of optical wavelengths, which have attracted tremendous research interest particularly in biological applications in the past decade. Compared to conventional noble metal-based plasmonic materials, plasmonic metal oxides are particularly favored for their cost efficiency, flexible plasmonic properties, and improved biocompatibility, which can be important to accelerate their practical implementation. In this review, we first explicate the origin of plasmonics in dopant/defect-enabled metal oxides and their associated tunable localized surface plasmon resonance through the conventional Mie-Gans model. The research progress of dopant incorporation and defect generation in metal oxide hosts, including both and approaches, is critically discussed. The implementation of plasmonic metal oxides in biological applications in terms of therapy, imaging, and sensing is summarized, in which the uniqueness of dopant/defect-driven plasmonics for inducing novel functionalities is particularly emphasized. This review may provide insightful guidance for developing next-generation plasmonic devices for human health monitoring, diagnosis and therapy.
金属氧化物掺杂和缺陷改性是一类新兴的新型材料，支持在广泛的光学波长范围内产生局域表面等离子体共振，在过去十年中，它们在生物应用中引起了极大的研究兴趣。与传统的基于贵金属的等离子体材料相比，等离子体金属氧化物特别受青睐，因为它们具有成本效益、灵活的等离子体特性和改善的生物相容性，这对于加速其实际应用非常重要。在这篇综述中，我们首先通过传统的 Mie-Gans 模型解释了掺杂/缺陷金属氧化物中等离子体的起源及其相关的可调谐局域表面等离子体共振。我们批判性地讨论了金属氧化物宿主中掺杂剂掺入和缺陷产生的研究进展，包括 和 方法。总结了等离子体金属氧化物在治疗、成像和传感等生物应用中的实施情况，特别强调了掺杂/缺陷驱动等离子体在诱导新功能方面的独特性。这篇综述可能为开发用于人体健康监测、诊断和治疗的下一代等离子体器件提供有见地的指导。
