Department of Psychology, Columbia University, New York, United States.
Elife. 2022 Jul 5;11:e69430. doi: 10.7554/eLife.69430.
How does the representation of naturalistic life events change with age? Here, we analyzed fMRI data from 414 children and adolescents (5-19 years) as they watched a narrative movie. In addition to changes in the degree of inter-subject correlation (ISC) with age in sensory and medial parietal regions, we used a novel measure (between-group ISC) to reveal age-related shifts in the responses across the majority of the neocortex. Over the course of development, brain responses became more discretized into stable and coherent events and shifted earlier in time to anticipate upcoming perceived event transitions, measured behaviorally in an age-matched sample. However, hippocampal responses to event boundaries actually decreased with age, suggesting a shifting division of labor between episodic encoding processes and schematic event representations between the ages of 5 and 19.
自然主义生活事件的表现如何随年龄变化？在这里，我们分析了 414 名儿童和青少年（5-19 岁）在观看叙事电影时的 fMRI 数据。除了在感觉和内侧顶叶区域中与年龄相关的个体间相关性（ISC）程度的变化之外，我们还使用了一种新的测量方法（组间 ISC）来揭示整个新皮层中与年龄相关的反应变化。在整个发育过程中，大脑反应变得更加离散为稳定和连贯的事件，并更早地转移时间以预测即将到来的感知事件转变，在年龄匹配的样本中进行行为测量。然而，海马体对事件边界的反应实际上随着年龄的增长而下降，这表明在 5 至 19 岁之间，情节编码过程和示意性事件表示之间的分工发生了转变。
