Princeton Neuroscience Institute and Department of Psychology, Princeton University, Princeton, NJ 08544, USA.
Social Brain Lab, Netherlands Institute for Neuroscience, KNAW, 105BA Amsterdam, The Netherlands.
Soc Cogn Affect Neurosci. 2019 Aug 7;14(6):667-685. doi: 10.1093/scan/nsz037.
Our capacity to jointly represent information about the world underpins our social experience. By leveraging one individual's brain activity to model another's, we can measure shared information across brains-even in dynamic, naturalistic scenarios where an explicit response model may be unobtainable. Introducing experimental manipulations allows us to measure, for example, shared responses between speakers and listeners or between perception and recall. In this tutorial, we develop the logic of intersubject correlation (ISC) analysis and discuss the family of neuroscientific questions that stem from this approach. We also extend this logic to spatially distributed response patterns and functional network estimation. We provide a thorough and accessible treatment of methodological considerations specific to ISC analysis and outline best practices.
我们共同表示关于世界的信息的能力是我们社会经验的基础。通过利用一个人的大脑活动来模拟另一个人的大脑活动,我们可以在动态的自然场景中测量大脑之间的共享信息,即使在无法获得明确反应模型的情况下也是如此。引入实验操作可以让我们测量例如说话者和听众之间或感知和回忆之间的共享反应。在本教程中,我们发展了主体间相关性(ISC)分析的逻辑,并讨论了由此方法产生的一系列神经科学问题。我们还将此逻辑扩展到空间分布的响应模式和功能网络估计。我们对 ISC 分析特有的方法学考虑因素进行了彻底和易于理解的处理,并概述了最佳实践。