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基于机器学习的血清维生素 D 与脑梗死患者神经功能缺损的预测模型。

Prediction Model between Serum Vitamin D and Neurological Deficit in Cerebral Infarction Patients Based on Machine Learning.

机构信息

Department of Neurology, Cangzhou Central Hospital, Cangzhou 061000, China.

出版信息

Comput Math Methods Med. 2022 Jun 28;2022:2914484. doi: 10.1155/2022/2914484. eCollection 2022.

DOI:10.1155/2022/2914484
PMID:35799673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9256304/
Abstract

OBJECTIVE

Vitamin D is associated with neurological deficits in patients with cerebral infarction. This study uses machine learning to evaluate the prediction model's efficacy of the correlation between vitamin D and neurological deficit in patients with cerebral infarction.

METHODS

A total of 200 patients with cerebral infarction admitted to the Department of Neurology of our hospital from July 2018 to June 2019 were selected. The patients were randomly divided into a training set ( = 140) and a test set ( = 60) in a 7 : 3 ratio. The prediction model is constructed from the training set's data, and the model's prediction effect was evaluated by test set data. The area under the receiver operator characteristic curve was used to assess the prediction efficiency of models.

RESULTS

In the training set, the area under the curve (AUC) of the logistic regression model and XGBoost algorithm model was 0.727 (95% CI: 0.6010.854) and 0.818 (95% CI: 0.7340.934), respectively. While in the test set, the AUC of the logistic regression model and XGBoost algorithm model was 0.761 (95% CI: 0.6400.882) and 0.786 (95% CI: 0.6700.902), respectively.

CONCLUSION

The prediction model of the correlation between vitamin D and neurological deficit in patients with cerebral infarction based on machine learning has a good prediction efficiency.

摘要

目的

维生素 D 与脑梗死患者的神经功能缺损有关。本研究采用机器学习评估维生素 D 与脑梗死患者神经功能缺损相关性预测模型的效能。

方法

选取 2018 年 7 月至 2019 年 6 月我院神经内科收治的 200 例脑梗死患者,采用随机数字表法将患者分为训练集(n = 140)和测试集(n = 60),两组比例为 7∶3。从训练集的数据中构建预测模型,采用测试集数据评价模型的预测效果。采用受试者工作特征曲线下面积评估模型的预测效能。

结果

在训练集中,逻辑回归模型和 XGBoost 算法模型的曲线下面积(AUC)分别为 0.727(95%CI:0.6010.854)和 0.818(95%CI:0.7340.934)。而在测试集中,逻辑回归模型和 XGBoost 算法模型的 AUC 分别为 0.761(95%CI:0.6400.882)和 0.786(95%CI:0.6700.902)。

结论

基于机器学习的脑梗死患者维生素 D 与神经功能缺损相关性预测模型具有较好的预测效能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/877044b3f07b/CMMM2022-2914484.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/8cbbf9acc4d9/CMMM2022-2914484.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/3fee1e3ef0cd/CMMM2022-2914484.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/d111ffa0932f/CMMM2022-2914484.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/dc21a2dd811e/CMMM2022-2914484.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/877044b3f07b/CMMM2022-2914484.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/8cbbf9acc4d9/CMMM2022-2914484.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/3fee1e3ef0cd/CMMM2022-2914484.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/d111ffa0932f/CMMM2022-2914484.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/dc21a2dd811e/CMMM2022-2914484.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/9256304/877044b3f07b/CMMM2022-2914484.005.jpg

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本文引用的文献

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2
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Lancet Diabetes Endocrinol. 2021 Dec;9(12):837-846. doi: 10.1016/S2213-8587(21)00263-1. Epub 2021 Oct 28.
3
Incidence of Cerebral Infarction in Northwest China From 2009 to 2018.
基于机器学习构建缺血性中风患者不良出院结局预测模型
Heliyon. 2024 Sep 1;10(17):e37179. doi: 10.1016/j.heliyon.2024.e37179. eCollection 2024 Sep 15.
4
Development of machine learning-based models for predicting risk factors in acute cerebral infarction patients: a clinical retrospective study.基于机器学习的急性脑梗死患者危险因素预测模型的构建:一项临床回顾性研究。
BMC Neurol. 2024 Aug 31;24(1):306. doi: 10.1186/s12883-024-03818-6.
5
Vitamin D: An Essential Nutrient in the Dual Relationship between Autoimmune Thyroid Diseases and Celiac Disease-A Comprehensive Review.维生素 D:在自身免疫性甲状腺疾病和乳糜泻的双重关系中不可或缺的营养物质——全面综述
Nutrients. 2024 Jun 4;16(11):1762. doi: 10.3390/nu16111762.
6
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Mol Biotechnol. 2023 Aug;65(8):1336-1345. doi: 10.1007/s12033-022-00643-5. Epub 2022 Dec 27.
2009年至2018年中国西北地区脑梗死发病率
Cureus. 2021 Aug 30;13(8):e17576. doi: 10.7759/cureus.17576. eCollection 2021 Aug.
4
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J Comput Biol. 2021 Jul;28(7):687-700. doi: 10.1089/cmb.2020.0543. Epub 2021 Jun 21.
5
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Exp Neurol. 2021 Aug;342:113752. doi: 10.1016/j.expneurol.2021.113752. Epub 2021 May 8.
6
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7
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Histol Histopathol. 2021 Feb;36(2):143-158. doi: 10.14670/HH-18-253. Epub 2020 Sep 30.
8
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Neuropharmacology. 2020 Dec 15;181:108327. doi: 10.1016/j.neuropharm.2020.108327. Epub 2020 Sep 18.
9
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Molecules. 2020 Jul 15;25(14):3219. doi: 10.3390/molecules25143219.
10
Cholecalciferol or Calcifediol in the Management of Vitamin D Deficiency.胆钙化醇或钙三醇在维生素 D 缺乏症管理中的应用。
Nutrients. 2020 May 31;12(6):1617. doi: 10.3390/nu12061617.