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新型冠状病毒肺炎与巨细胞动脉炎的重叠症状:诊断鉴别时需要更高程度的怀疑。

Overlapping Symptoms of COVID-19 and Giant Cell Arteritis: The Need for a Higher Degree of Suspicion for Diagnostic Differentiation.

作者信息

Aryal Binit, Kadakia Nevil, Baniya Aashish, Chowdhury Tutul, Adhikari Samaj, Gousy Nicole

机构信息

Internal Medicine, Interfaith Medical Center, Brooklyn, USA.

Neurology, Upendra Devkota Memorial National Institute of Neurological and Allied Sciences (UDM-NINAS), Kathmandu, NPL.

出版信息

Cureus. 2022 Jun 4;14(6):e25660. doi: 10.7759/cureus.25660. eCollection 2022 Jun.

DOI:10.7759/cureus.25660
PMID:35800189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9252443/
Abstract

Giant cell arteritis (GCA) is a large cell vasculitis that can present with a plethora of symptoms affecting several different systems. Before the COVID-19 pandemic, diagnosis of GCA was straightforward since the list of differential diagnoses for this disease was relatively short. However, the development of a SARS-CoV-2 viral infection challenges this standard. COVID-19 is a viral illness that also can present with similar vascular symptoms as GCS and creates a substantial inflammatory reaction, similar to most vasculitis. We present a case of a patient who had developed GCA after recovering from a COVID-19 viral illness. This is a rare presentation of GCA in the setting of COVID-19, and recognition of the nuanced differences between the two diseases may significantly change a patient's prognosis if not detected early.

摘要

巨细胞动脉炎(GCA)是一种大细胞血管炎,可表现出影响多个不同系统的多种症状。在2019冠状病毒病(COVID-19)大流行之前,GCA的诊断很简单,因为该疾病的鉴别诊断清单相对较短。然而,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒感染的出现对这一标准提出了挑战。COVID-19是一种病毒性疾病,也可表现出与GCA相似的血管症状,并引发与大多数血管炎类似的强烈炎症反应。我们报告一例患者,其在从COVID-19病毒性疾病康复后患上了GCA。这是COVID-19背景下GCA的罕见表现,如果不及早发现,认识到这两种疾病之间的细微差异可能会显著改变患者的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a423/9252443/d65abc031b85/cureus-0014-00000025660-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a423/9252443/d65abc031b85/cureus-0014-00000025660-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a423/9252443/d65abc031b85/cureus-0014-00000025660-i01.jpg

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Clin Rheumatol. 2022 Aug;41(8):2449-2456. doi: 10.1007/s10067-022-06157-4. Epub 2022 Apr 2.
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Advances in the Treatment of Giant Cell Arteritis.巨细胞动脉炎的治疗进展
J Clin Med. 2022 Mar 13;11(6):1588. doi: 10.3390/jcm11061588.
3
Clinical pathways for patients with giant cell arteritis during the COVID-19 pandemic: an international perspective.2019冠状病毒病大流行期间巨细胞动脉炎患者的临床路径:国际视角
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Diagnostic Accuracy of Symptoms, Physical Signs, and Laboratory Tests for Giant Cell Arteritis: A Systematic Review and Meta-analysis.巨细胞动脉炎的症状、体征和实验室检查的诊断准确性:系统评价和荟萃分析。
JAMA Intern Med. 2020 Oct 1;180(10):1295-1304. doi: 10.1001/jamainternmed.2020.3050.
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