Walicka Magdalena, Russo Cristina, Baxter Michael, John Isaac, Caci Grazia, Polosa Riccardo
Department of Human Epigenetics, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw 02-106, Poland.
Ashford and Saint Peter's Hospitals NHS Foundation Trust, Chertsey KT16 0PZ, United Kingdom.
World J Diabetes. 2022 Jun 15;13(6):422-433. doi: 10.4239/wjd.v13.i6.422.
The purpose of this scoping review is to create a single narrative that describes the impact of smoking cessation on metabolic parameters in people with diabetes. It is generally well accepted that smoking enhances the harmful effects of elevated blood glucose levels, accelerating the vascular damage seen in patients with diabetes. Smoking cessation has clear benefits in terms of reducing cardiovascular morbidity and mortality. However, there is less evidence for the impact of smoking cessation on other diabetes-related complications. Studies in people with diabetes have shown improvement as well as temporary deterioration in glycemic control after ceasing smoking. Only a few studies have described the effect of quitting smoking on insulin resistance and lipid parameters, however, their results have been inconclusive. In this situation, healthcare professionals should not assume that cessation of smoking will improve metabolic parameters in patients with diabetes. It seems they should, first of all, emphasize the prevention of weight gain that may be associated with quitting smoking. The lack of data regarding the metabolic effects of smoking and smoking cessation in diabetes is very disappointing and this area needs to be addressed.
本综述的目的是形成一个单一的叙述,描述戒烟对糖尿病患者代谢参数的影响。人们普遍认为,吸烟会增强血糖升高的有害影响,加速糖尿病患者出现的血管损伤。戒烟在降低心血管发病率和死亡率方面有明显益处。然而,关于戒烟对其他糖尿病相关并发症影响的证据较少。对糖尿病患者的研究表明,戒烟后血糖控制有改善也有暂时恶化的情况。只有少数研究描述了戒烟对胰岛素抵抗和血脂参数的影响,然而,其结果尚无定论。在这种情况下,医疗保健专业人员不应假定戒烟会改善糖尿病患者的代谢参数。似乎他们首先应该强调预防可能与戒烟相关的体重增加。关于吸烟及戒烟对糖尿病代谢影响的数据匮乏非常令人失望,这一领域需要得到关注。