乳腺癌的组织学分级、弹性组织变性、DNA倍体及对化疗的反应
Histological grade, elastosis, DNA ploidy and the response to chemotherapy of breast cancer.
作者信息
Masters J R, Camplejohn R S, Millis R R, Rubens R D
出版信息
Br J Cancer. 1987 Apr;55(4):455-7. doi: 10.1038/bjc.1987.89.
Abstract
The relationships between response to chemotherapy of advanced breast cancer and the histological type, grade, elastosis content and DNA ploidy of the primary tumours were examined using paraffin-embedded tissue derived from 125 patients. Higher response rates were seen amongst tumours with a high elastosis content and those that were diploid. However, selection of patients with advanced breast cancer for chemotherapy will not be assisted significantly by an assessment of these features in the primary tumour.
摘要
利用取自125例患者的石蜡包埋组织，研究了晚期乳腺癌化疗反应与原发肿瘤的组织学类型、分级、弹性组织含量和DNA倍体之间的关系。在弹性组织含量高的肿瘤和二倍体肿瘤中观察到较高的反应率。然而，对原发肿瘤这些特征的评估对晚期乳腺癌患者化疗的选择并无显著帮助。
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