Department of Midwifery, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Reprod Health. 2022 Jul 8;19(1):157. doi: 10.1186/s12978-022-01463-1.
The burden of pre-eclampsia has been continued as a public health importance in both developed and developing countries. However, the consequence of the disease is significantly high in developing countries, where treatment may be unsuccessful due to unclear etiology and late presentation of cases. The determinants of pre-eclampsia are not well known in the Ethiopian population specifically in the study area. Therefore, this study was aimed to identify the determinant factors of pre-eclampsia among women attending delivery services in public health institutions of Debre Tabor Town.
Unmatched case-control study was conducted from December 1, 2020, to January 15, 2021, among 264 mothers (88 cases and 176 controls). A case-control incidence density sampling technique was applied and data were collected using an interviewer-administered pre-tested questionnaire. Data were entered using Epi-data version 4.2 and analyzed by statistical package for social science (SPSS) version 23. Bivariate and multivariable logistic regression analyses were conducted. Finally, a significant association was declared at a p-value of ≤ 0.05 with 95% CI.
Young age at menarche (10-15 years) (AOR: 7.69; 95% CI: 3.10-25.29), status of the current pregnancy (AOR: 5.88; 95% CI:2.93-22.42), new partner (AOR: 4.16; 95% CI: 3.49-17.03), family history of pre-eclampsia (AOR: 1.52; 95% CI: 1.40-4.18), and alcohol drinking (AOR: 2.18; 95% CI: 2.04-11.79) were found to be significantly associated with pre-eclampsia.
The current study identified that young age at menarche, the status of current pregnancy, new partner, family history of pre-eclampsia, and alcohol drinking were some of the determinant factors of pre-eclampsia. We suggested that health care providers should use these identified factors as a screening means for prediction, early diagnoses, and timely interventions of pre-eclampsia. Health care professionals should also deliver information regarding the risk of alcohol drinking during pregnancy in the preconception period and at early antenatal care services.
子痫前期的负担在发达国家和发展中国家仍然是一个公共卫生重点。然而，在发展中国家，这种疾病的后果非常严重，由于病因不明和病例出现较晚，治疗可能不成功。在埃塞俄比亚人群中，特别是在研究地区，子痫前期的决定因素尚不清楚。因此，本研究旨在确定德布雷塔博尔镇公立医疗机构分娩服务的妇女中子痫前期的决定因素。
2020 年 12 月 1 日至 2021 年 1 月 15 日，采用 264 名母亲（88 例病例和 176 例对照）进行了非匹配病例对照研究。采用病例对照发生率密度抽样技术，使用访谈者管理的预测试问卷收集数据。数据使用 EpiData 版本 4.2 输入，并使用社会科学统计软件包（SPSS）版本 23 进行分析。进行了单变量和多变量逻辑回归分析。最后，以 p 值≤0.05 和 95%置信区间表示具有统计学意义的关联。
初潮年龄为 10-15 岁（AOR：7.69；95%CI：3.10-25.29）、当前妊娠状态（AOR：5.88；95%CI：2.93-22.42）、新伴侣（AOR：4.16；95%CI：3.49-17.03）、子痫前期家族史（AOR：1.52；95%CI：1.40-4.18）和饮酒（AOR：2.18；95%CI：2.04-11.79）与子痫前期显著相关。
本研究发现，初潮年龄较小、当前妊娠状态、新伴侣、子痫前期家族史和饮酒是子痫前期的一些决定因素。我们建议卫生保健提供者将这些确定的因素用作预测、早期诊断和子痫前期及时干预的筛查手段。卫生保健专业人员还应在孕前和早期产前保健服务期间提供有关怀孕期间饮酒风险的信息。
