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[具体物质]对断奶仔猪生长性能、腹泻发生率、抗氧化能力、免疫功能及粪便微生物区系的影响

Effects of on Growth Performance, Diarrhea Incidence, Antioxidant Capacity, Immune Function, and Fecal Microflora in Weaned Piglets.

作者信息

Yu Xiaorong, Cui Zhenchuan, Qin Songke, Zhang Ruiqiang, Wu Yanping, Liu Jinsong, Yang Caimei

机构信息

College of Animal Science and Technology, College of Animal Medicine, Zhejiang Agriculture & Forestry University, Hangzhou 311300, China.

Key Laboratory of Molecular Animal Nutrition (Zhejiang University), Ministry of Education, Hangzhou 311300, China.

出版信息

Animals (Basel). 2022 Jun 22;12(13):1609. doi: 10.3390/ani12131609.

Abstract

() is a safe probiotic that can promote animal growth and inhibit pathogenic bacteria. This study aimed to assess the effects of , one green feed additive, on growth performance, diarrhea incidence, immune function, fecal volatile fatty acids, and microflora structure in weaned piglets. Weaned piglets ( = 180) were randomly divided into three treatment groups and fed a basal diet and a basal diet supplemented with 500 mg per kg and 1000 mg per kg, respectively. The dietary 500 mg/kg inclusion improved the average daily gain, reduced diarrhea incidence, and strengthened antioxidant capacity. Piglets supplemented with presented increased serum immunoglobulins (IgA, IgM) compared to the CON group. Meanwhile, the expression of anti-inflammation factors was increased, and the levels of pro-inflammation factors were reduced after administration. Moreover, the levels of volatile fatty acids, including acetic acid, propionic acid, butyric acid, isobutyric acid, and isovaleric acid, in the BL500 and BL1000 groups were increased compared with the CON group, and the concentration of valeric acid was higher in the BL500 group. Furthermore, piglets in the 500 mg/kg addition group significantly altered fecal microbiota by increasing and . In conclusion, dietary relieved diarrhea, enhanced antioxidant capacity, immunity function, and fecal microflora structure in weaned pigs.

摘要

()是一种安全的益生菌,可促进动物生长并抑制病原菌。本研究旨在评估一种绿色饲料添加剂()对断奶仔猪生长性能、腹泻发生率、免疫功能、粪便挥发性脂肪酸和微生物区系结构的影响。将180头断奶仔猪随机分为三个处理组,分别饲喂基础日粮以及添加每千克500毫克()和每千克1000毫克()的基础日粮。日粮中添加500毫克/千克()可提高平均日增重、降低腹泻发生率并增强抗氧化能力。与对照组相比,添加()的仔猪血清免疫球蛋白(IgA、IgM)增加。同时,给药后抗炎因子的表达增加,促炎因子水平降低。此外,与对照组相比,BL500组和BL1000组中包括乙酸、丙酸、丁酸、异丁酸和异戊酸在内的挥发性脂肪酸水平升高,且BL500组中戊酸浓度更高。此外,添加500毫克/千克()组的仔猪通过增加()和()显著改变了粪便微生物群。总之,日粮添加()可缓解断奶仔猪腹泻,增强其抗氧化能力、免疫功能和粪便微生物区系结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda1/9264952/c54c93c12669/animals-12-01609-g001.jpg

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