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一种简单的复制方法作为获得形态和力学性能类似骨的铁基可生物降解材料的途径。

A Simple Replica Method as the Way to Obtain a Morphologically and Mechanically Bone-like Iron-Based Biodegradable Material.

作者信息

Grodzicka Marlena, Gąsior Gabriela, Wiśniewski Marek, Bartmański Michał, Radtke Aleksandra

机构信息

Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina Street 7, 87-100 Toruń, Poland.

Faculty of Mechanical Engineering and Ship Technology, Gdańsk University of Technology, Narutowicza Street 11/12, 80-233 Gdańsk, Poland.

出版信息

Materials (Basel). 2022 Jun 28;15(13):4552. doi: 10.3390/ma15134552.

Abstract

Porous iron-based scaffolds were prepared by the simple replica method using polyurethane foam as a template and applying the sintering process in a tube furnace. Their surface morphology was characterized using scanning electron microscopy (SEM) and phase homogeneity was confirmed using X-ray diffraction (XRD). Corrosion behavior was determined using immersion and potentiodynamic polarization methods in phosphate buffered saline (PBS). The surface energy was calculated by studying the changes of enthalpy of calorimetric immersion. A preliminary biological test was also carried out and was done using the albumin adsorption procedure. Results of our work showed that in using the simple replica method it is possible to obtain iron biomaterial with morphology and mechanical properties almost identical to bones, and possessing adequate wettability, which gives the potential to use this material as biomaterial for scaffolds in orthopedics.

摘要

采用简单的复制法,以聚氨酯泡沫为模板,并在管式炉中进行烧结工艺,制备了多孔铁基支架。使用扫描电子显微镜(SEM)对其表面形态进行了表征,并使用X射线衍射(XRD)确认了相均匀性。在磷酸盐缓冲盐水(PBS)中,采用浸泡法和动电位极化法测定了腐蚀行为。通过研究量热浸没法中焓的变化来计算表面能。还进行了初步的生物学测试,采用白蛋白吸附程序完成。我们的工作结果表明,使用简单的复制法可以获得形态和力学性能与骨骼几乎相同、具有足够润湿性的铁生物材料,这使得该材料有潜力用作骨科支架的生物材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8845/9267498/dd2318fc1b06/materials-15-04552-g001.jpg

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