Department of Pharmaceutical Microbiology and Parasitology, Medical University of Wroclaw, 50-367 Wroclaw, Poland.
Division of Pharmaceutical Biotechnology, Department of Pharmaceutical Biology and Biotechnology, Medical University of Wroclaw, 50-367 Wroclaw, Poland.
Molecules. 2022 Jun 25;27(13):4096. doi: 10.3390/molecules27134096.
is an opportunistic pathogen causing life-threatening, hard-to-heal infections associated with the presence of a biofilm. Essential oils (EOs) are promising agents to combat pseudomonal infections because of the alleged antimicrobial activity of their volatile fractions and liquid forms. Therefore, the purpose of this paper was to evaluate the antibacterial efficacy of both volatile and liquid phases of seven EOs (thyme, tea tree, basil, rosemary, eucalyptus, menthol mint, lavender) against biofilm and planktonic cells with the use of a broad spectrum of analytical in vitro methods. According to the study results, the antibacterial activity of EOs in their liquid forms varied from that of the volatile fractions. Overall, liquid and volatile forms of rosemary EO and tea tree EO displayed significant antibiofilm effectiveness. The outcomes indicate that these particular EOs possess the potential to be used in the therapy of infections.
是一种机会性病原体，可导致与生物膜存在相关的危及生命、难以治愈的感染。由于其挥发性成分和液体形式据称具有抗菌活性，因此精油（EOs）是对抗假单胞菌感染的有前途的药物。因此，本文的目的是使用广泛的体外分析方法评估七种 EO（百里香、茶树、罗勒、迷迭香、桉树、薄荷脑、薰衣草）的挥发性和液相在对抗生物膜和浮游细胞方面的抗菌功效。根据研究结果，EO 在其液体形式中的抗菌活性与其挥发性成分不同。总体而言，迷迭香精油和茶树精油的液体和挥发性形式均显示出显著的抗生物膜效果。研究结果表明，这些特定的 EO 具有在 感染治疗中应用的潜力。
