Parkin A, Wiggins P A, Robinson P J, Vowden P, Kester R C, Ware F M
Br J Surg. 1987 Apr;74(4):271-4. doi: 10.1002/bjs.1800740415.
A method for measuring limb blood flow during reactive hyperaemia is described. Pneumatic cuffs inflated to 300 mmHg are used to isolate the blood in the limbs from the rest of the circulation. The remaining blood is labelled with technetium. The increase in radioactivity in the limb following release of the cuffs is measured using a gamma camera. The mean rate of flow of blood to the limb (in ml (100 ml)-1 tissue min-1) is derived from the graph of radioactivity versus time and from the radioactivity in a sample of venous blood. The results of measurements carried out in patients with peripheral vascular disease (30 limbs) and normal controls (24 limbs) are presented. Repeated studies in 10 subjects (20 limbs) showed the method to be highly reproducible at high and low flow rates (r = 0.99). Case studies illustrating the use of the method as a screening test for peripheral vascular disease and to monitor the effects of treatment are presented.
本文描述了一种测量反应性充血期间肢体血流的方法。使用充气至300 mmHg的气动袖带将肢体中的血液与循环系统的其余部分隔离开来。其余血液用锝标记。使用γ相机测量松开袖带后肢体中放射性的增加。肢体的平均血流速率（以ml(100 ml)-1组织min-1为单位）由放射性与时间的关系图以及静脉血样本中的放射性得出。给出了对周围血管疾病患者（30条肢体）和正常对照者（24条肢体）进行测量的结果。对10名受试者（20条肢体）进行的重复研究表明，该方法在高流量和低流量下具有高度可重复性（r = 0.99）。还给出了案例研究，说明该方法作为周围血管疾病筛查试验以及监测治疗效果的应用。
