Department of Sports Medicine, University of Wuppertal, Wuppertal, Germany.
Eur J Appl Physiol. 2022 Oct;122(10):2213-2222. doi: 10.1007/s00421-022-04997-1. Epub 2022 Jul 9.
Acute physical activity leads to exercise-induced hypoalgesia (EIH). The aim of this study was to investigate the effects of four different exercise intensities on EIH.
25 male (age: 24.7 ± 3.0) subjects underwent four different exercise sessions on a bicycle ergometer for 30 min each at 60, 80, 100, and 110% of the individual anaerobic threshold on separate days in a randomized crossover design. Before, as well as 5- and 45-min post-exercise, pain sensitivity was measured employing pain pressure thresholds (PPT) at the elbow, knee, and ankle joints as well as the sternum and forehead. Besides, conditioned pain modulation (CPM) was conducted using thermal test- and conditioned stimuli before, 5-, and 45-min post-exercise.
A main time effect was observed regarding PPT at all landmarks except for the forehead with higher values observed 5 and 45 min post-exercise compared to the pre-values. Yet, no interaction effects occurred. CPM did not change in response to any of the intensities used.
EIH occurs 5 and 45 min after exercise regardless of the intensity used at the joints and sternum which might be explained by local pain-inhibiting pathways and probably to a limited degree by central mechanisms, as no hypoalgesia was observed at the forehead and no changes in CPM occurred.
急性身体活动会导致运动诱导性痛觉减退（EIH）。本研究旨在探讨四种不同运动强度对 EIH 的影响。
25 名男性（年龄：24.7±3.0）在 4 个不同的日子里，按照随机交叉设计，分别在自行车测功计上进行 30 分钟的 60%、80%、100%和 110%个体无氧阈的 4 种不同的运动强度。在运动前、运动后 5 分钟和 45 分钟，测量肘部、膝盖、脚踝和胸骨及额头关节的疼痛压力阈值（PPT）来评估痛觉敏感度。此外，在运动前、运动后 5 分钟和 45 分钟，通过热测试和条件刺激进行条件性疼痛调制（CPM）。
除了额头外，所有部位的 PPT 在所有时间点都观察到了主要的时间效应，与运动前相比，运动后 5 分钟和 45 分钟的 PPT 值更高。然而，没有观察到交互作用效应。CPM 没有因使用的任何强度而发生变化。
EIH 发生在运动后 5 分钟和 45 分钟，无论使用的关节和胸骨强度如何，这可能是由于局部疼痛抑制途径，可能在一定程度上由于中枢机制，因为在额头没有观察到痛觉减退，CPM 也没有发生变化。
