[植物名称]茎的化学成分及其生物活性。 需注意，原文中“of and their bioactivities”部分有缺失信息，这里补充了“[植物名称]”以使译文更完整通顺。
Chemical constituents of the stem of and their bioactivities.
作者信息
Gurgul Aleksandra, Nauman Mirielle C, Wu Zhenlong, Shetye Gauri, Ma Rui, Youn Isoo, Souliya Onevilay, Bisson Jonathan, Johnson Jeremy J, Che Chun-Tao
机构信息
Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, China.
出版信息
Nat Prod Res. 2023 Oct-Nov;37(21):3623-3630. doi: 10.1080/14786419.2022.2097229. Epub 2022 Jul 12.
Phytochemical investigation of (Annonaceae) led to the isolation of a new phenylpropanoid glycoside, lyciumphenylpropanoid B (), along with nine known compounds (-) from an aqueous methanolic extract of the stem. Most compounds are reported from this genus for the first time. The structures of the isolated compounds were elucidated using spectroscopic methods including NMR spectroscopy, high-resolution mass spectrometry, and quantum chemical electronic circular dichroism (ECD) calculations. Cytotoxic and antitubercular activities of several isolated compounds were evaluated. Dipyrithione () displayed anti-mycobacterial (MIC = 0.23 μM) and cytotoxic (IC = 0.8 μM in Hep G2 cells; 4.1 μM in HCT 116 cells) activities. Kelampayoside A () showed moderate cytotoxic activity against cancer cells.
对（番荔枝科）进行植物化学研究，从其茎的甲醇水提取物中分离出一种新的苯丙素苷——枸杞苯丙素B（），以及九种已知化合物（-）。大多数化合物首次从该属植物中报道。通过包括核磁共振光谱、高分辨率质谱和量子化学电子圆二色性（ECD）计算在内的光谱方法阐明了分离出的化合物的结构。评估了几种分离出的化合物的细胞毒性和抗结核活性。二硫吡啶酮（）表现出抗分枝杆菌活性（MIC = 0.23 μM）和细胞毒性（在Hep G2细胞中IC = 0.8 μM；在HCT 116细胞中为4.1 μM）。Kelampayoside A（）对癌细胞表现出中等程度的细胞毒性活性。
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