全谷物饮食对老年人肠道微生物群的影响。
The Effect of Whole-Grain Diet on the Gut Microbiota of the Elderly Individuals.
作者信息
Cui Zeying, Li Jingtai, Zhen Yuting, Fan Pingming, Du Guankui
机构信息
Department of Breast Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Key Laboratory of Molecular Biology, Hainan Medical University, Haikou, China.
出版信息
Front Nutr. 2022 Jun 27;9:919838. doi: 10.3389/fnut.2022.919838. eCollection 2022.
A whole-grain (WG) diet affects human health in multiple ways. However, the effect of WG on the gut microbiota of the elderly individuals is still largely unknown. In this study, WG did not affect the microbial α-diversity but had a profound impact on the microbes' abundance in the elderly individuals. WG increased the abundance of and decreased the abundance of . The prediction of microbial function showed that glucose metabolism and lipid metabolism were inhibited. In addition, the effects of WG on the gut microbiota of normal-weight (NW) and overweight (OW) individuals were different. WG increased in the NW group and decreased in the OW group. Meanwhile, the effect of WG on gut microbiota showed gender characteristics, ratio was decreased in women, while abundance was increased in men. The use of WG could improve the microbial composition and promote the growth of beneficial microbes, which may be beneficial to the health of the elderly individuals.
全谷物（WG）饮食对人类健康有多种影响。然而，WG对老年人肠道微生物群的影响在很大程度上仍不清楚。在本研究中，WG不影响微生物α多样性，但对老年人的微生物丰度有深远影响。WG增加了[具体微生物名称1]的丰度并降低了[具体微生物名称2]的丰度。微生物功能预测表明葡萄糖代谢和脂质代谢受到抑制。此外，WG对正常体重（NW）和超重（OW）个体肠道微生物群的影响不同。WG在NW组中增加了[具体微生物名称3]，在OW组中降低了[具体微生物名称4]。同时，WG对肠道微生物群的影响呈现出性别特征，女性的[具体微生物比例1]降低，而男性的[具体微生物名称5]丰度增加。食用WG可以改善微生物组成并促进有益微生物的生长，这可能对老年人的健康有益。
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