Edjolo Arlette, Dorey Jean-Michel, Herrmann Mathieu, Perrot Catherine, Lebrun-Givois Cécile, Buisson Aurélie, El Haouari Hanane, Laurent Bernard, Pongan Elodie, Rouch Isabelle
CROMA, University Hospital of Saint-Etienne, Saint-Etienne, France.
INSERM, U1219, Bordeaux Population Health Center, University of Bordeaux, Bordeaux, France.
Front Psychiatry. 2022 Jun 27;13:918428. doi: 10.3389/fpsyt.2022.918428. eCollection 2022.
Due to the lockdown linked to the COVID-19 pandemic, the French National Authority for Health has recommended reinforced follow-up of psychiatric patients, with particular attention to people over 65 years. Cross-sectional studies reported an increased risk of anxiety, depression, and suicide during this period. Older people with psychiatric disorders are at higher risk of developing severe COVID-19 and worsening their psychiatric symptoms.
The main objective is to evaluate the link between coping strategies and the onset of post-traumatic stress disorder (PTSD) after lockdown. The secondary objective is to assess the psychological factors influencing lockdown experiences such as personality, attachment type, or coping strategies.
METHOD/DESIGN: this is a multicenter cohort study including 117 patients followed up by phone in two French geriatric psychiatry units. Sociodemographic variables, psychiatric diagnoses, lockdown conditions, coping strategies, anxiety, and depressive symptoms reported during the first lockdown will be collected retrospectively from the medical file. A first prospective assessment including personality traits, attachment type, and traumatic life events will be conducted at 12 months (T1). Follow-up visits assessing anxious-depressive symptoms and PTSD will be made 18 (T2) and 24 months (T3) after the first lockdown. The primary outcome measure is PTSD symptoms. Secondary outcomes measures are coping strategies, generalized anxiety, anxiety about the COVID-19 pandemic, and quality of life.
This study aims to determine if the type of coping strategies usually employed have an impact on the onset of PTSD after a lockdown period. It will also determine if these coping strategies are influenced by other factors such as sociodemographic variables, lockdown conditions, particular personality traits, attachment type, and traumatic life events. This study could help identify factors associated with a poorer experience of lockdowns and pandemic crisis in elderly patients followed in a psychiatric center, and guide support in future similar situations.
ClinicalTrials.gov: http://clinicaltrials.gov/show/NCT04760795, Registered 18 February 2021.
由于与新冠疫情相关的封锁措施，法国国家卫生管理局建议加强对精神病患者的随访，尤其要关注65岁以上人群。横断面研究报告称，在此期间焦虑、抑郁和自杀风险有所增加。患有精神疾病的老年人感染重症新冠病毒并使精神症状恶化的风险更高。
主要目的是评估应对策略与封锁解除后创伤后应激障碍（PTSD）发病之间的关联。次要目的是评估影响封锁经历的心理因素，如人格、依恋类型或应对策略。
方法/设计：这是一项多中心队列研究，纳入了法国两个老年精神病科通过电话随访的117名患者。将从医疗档案中回顾性收集社会人口统计学变量、精神科诊断、封锁情况、应对策略、首次封锁期间报告的焦虑和抑郁症状。在12个月时（T1）进行首次前瞻性评估，包括人格特质、依恋类型和创伤性生活事件。在首次封锁后的18个月（T2）和24个月（T3）进行随访，评估焦虑抑郁症状和创伤后应激障碍。主要结局指标是创伤后应激障碍症状。次要结局指标是应对策略、广泛性焦虑、对新冠疫情的焦虑和生活质量。
本研究旨在确定通常采用的应对策略类型是否会对封锁期后的创伤后应激障碍发病产生影响。还将确定这些应对策略是否受到其他因素的影响，如社会人口统计学变量、封锁情况、特定人格特质、依恋类型和创伤性生活事件。本研究有助于识别与精神病中心随访的老年患者封锁和大流行危机经历较差相关的因素，并为未来类似情况的支持提供指导。
ClinicalTrials.gov：http://clinicaltrials.gov/show/NCT04760795，2021年2月18日注册。
