Zhang Yuan, Liu Hai-Long, Tang Min, Wang Hui, Jiang Hui-Hong, Lin Mou-Bin
Department of General Surgery, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, P.R. China.
Department of Gynaecology and Obstetrics, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, P.R. China.
Exp Ther Med. 2022 Jun 17;24(2):525. doi: 10.3892/etm.2022.11452. eCollection 2022 Aug.
The present study investigated the characteristics, diagnosis, treatment and prognosis of hepatic portal venous gas (HPVG) using the data of 20 patients from the Tongji University School of Medicine Affiliated with Yangpu Hospital (Shanghai, China). The aim of the present study was to optimize the management method and improve the prognosis of patients with HPVG. A total of 20 patients were selected using a CT scan to confirm HPVG. All patients were enrolled and identified via a search engine, which examined all CT radiology reports containing the words pneumatosis and/or portal venous gas/air. Data were collected and analyzed, including sex, age, laboratory evidence, etiologies at admission, therapeutic method and in-hospital mortality. The patients consisted of 14 women (mean age, 79.1 years) and six men (mean age, 67.8 years). The results demonstrated that HPVG indicated a higher inflammatory index. The etiologies of HPVG included abdominal infection, pulmonary infection and hemorrhage, whereas the comorbidities included hypertension, diabetes, coronary disease, cerebrovascular disease and renal insufficiency. The present study determined that intestinal obstruction, acute enteritis and pulmonary infection were the main causes of HPVG. Of the 20 patients enrolled in the present study, four patients received surgery and 16 patients received conservative treatment. The overall in-hospital mortality was 25%. The present study indicated that the causes of HPVG may be closely related to inflammation and blood vessel injury. It was also determined that hemodynamic disorders of the intestinal tract and the combination of different types of infection were important contributors towards patient mortality.
本研究利用来自同济大学医学院附属杨浦医院（中国上海）的20例患者的数据，对肝门静脉气体（HPVG）的特征、诊断、治疗及预后进行了调查。本研究的目的是优化管理方法并改善HPVG患者的预后。通过CT扫描确诊HPVG，共选取了20例患者。所有患者均通过搜索引擎进行登记和识别，该引擎检索了所有包含“积气”和/或“门静脉气体/空气”字样的CT放射学报告。收集并分析了数据，包括性别、年龄、实验室证据、入院时的病因、治疗方法及院内死亡率。患者包括14名女性（平均年龄79.1岁）和6名男性（平均年龄67.8岁）。结果表明，HPVG提示炎症指标较高。HPVG的病因包括腹部感染、肺部感染和出血，而合并症包括高血压、糖尿病、冠心病、脑血管疾病和肾功能不全。本研究确定肠梗阻、急性肠炎和肺部感染是HPVG的主要原因。在本研究纳入的20例患者中，4例接受了手术，16例接受了保守治疗。总体院内死亡率为25%。本研究表明，HPVG的病因可能与炎症和血管损伤密切相关。还确定肠道血流动力学紊乱和不同类型感染的合并是导致患者死亡的重要因素。
