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镓-奥曲肽栓塞的正电子发射断层扫描/计算机断层扫描(PET/CT)表现及自发消退

Ga-DOTATOC Embolus Manifestation and Spontaneous Resolution by PET/CT.

作者信息

Al-Ibraheem Akram, Sweedat Deya' Aldeen, Anwer Farah, Istatieh Feras, Juweid Malik E

机构信息

Department of Nuclear Medicine, King Hussein Cancer Center, P.O. Box 1269 Al-Jubeiha, Amman, 11941 Jordan.

School of Medicine, The University of Jordan, Amman, Jordan.

出版信息

Nucl Med Mol Imaging. 2022 Aug;56(4):208-210. doi: 10.1007/s13139-022-00752-8. Epub 2022 May 12.

DOI:10.1007/s13139-022-00752-8
PMID:35846418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9276866/
Abstract

Ga-labeled somatostatin receptor analogs physiologic distribution patterns have become recognizable among nuclear medicine physicians because of the increasing routine clinical use of this modality in the work-up of neuroendocrine tumors. Some pitfalls during Ga-labeled somatostatin receptor PET/CT have recently been reported as causes of misdiagnoses. Iatrogenic microembolism as a cause of F-FDG embolus is well-established; however, 68Ga-DOTATOC embolus is not well documented in the literature. In the current case, the presence and the spontaneous resolution of the Ga-labeled somatostatin receptor analogs embolus during sequential PET/CT are nicely demonstrated. Awareness of this incidental finding would avoid misdiagnosis and unnecessary investigations.

摘要

由于镓标记的生长抑素受体类似物在神经内分泌肿瘤检查中的临床应用日益常规化,其生理分布模式已为核医学医生所熟知。最近有报道称,镓标记的生长抑素受体PET/CT检查过程中存在一些陷阱,可导致误诊。医源性微栓塞作为F-FDG栓子的病因已得到充分证实;然而,68Ga-DOTATOC栓子在文献中尚无充分记载。在本病例中,镓标记的生长抑素受体类似物栓子在连续PET/CT检查过程中的出现及自发消散得到了很好的展示。认识到这一偶然发现可避免误诊和不必要的检查。

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本文引用的文献

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Mol Imaging Radionucl Ther. 2021 Feb 9;30(1):39-46. doi: 10.4274/mirt.galenos.2021.37268.
2
Ga DOTA-TOC Uptake in Non-ossifying Fibroma: a Case Report.镓标记的DOTA-TOC在非骨化性纤维瘤中的摄取:一例报告
Nucl Med Mol Imaging. 2020 Aug;54(4):199-203. doi: 10.1007/s13139-020-00650-x. Epub 2020 Jul 6.
3
68Ga-DOTANOC Focal Pulmonary Activity With No Corresponding CT Abnormality.68Ga-DOTANOC 肺部局灶性摄取,而 CT 未见异常。
Clin Nucl Med. 2016 Dec;41(12):948-950. doi: 10.1097/RLU.0000000000001416.
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Radiographics. 2015 Mar-Apr;35(2):500-16. doi: 10.1148/rg.352140164.
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18F-FDG PET/CT lung 'focalities' without coregistered CT findings: an interpretative clinical dilemma.18F-FDG PET/CT检查发现肺部有“局灶性病变”但CT未发现相应表现:临床诊断的两难困境
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Focal uptake of 68Ga-DOTATOC in the pancreas: pathological or physiological correlate in patients with neuroendocrine tumours?胰腺中 68Ga-DOTATOC 的局灶摄取:神经内分泌肿瘤患者的病理或生理相关因素?
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