Zhao Hui, Feng Ya-Long, Wang Ming, Wang Jing-Jing, Liu Tian, Yu Jun
Clinical Experimental Center, Xi'an International Medical Center Hospital, Xi'an, China.
Xi'an Engineering Technology Research Center for Cardiovascular Active Peptides, Xi'an, China.
Front Pharmacol. 2022 Jul 1;13:896637. doi: 10.3389/fphar.2022.896637. eCollection 2022.
() root is a famous edible medicinal herb that has been used in China for thousands of years. To date, more than 300 chemical constituents have been discovered from . Among these ingredients, coumarins and volatile oils are the major active compounds. Moreover, a few other compounds have also been isolated from the root of , such as alkaloids, phenols, sterols, benzofurans, polyacetylenes and polysaccharides. Modern pharmacological studies demonstrated that the root of and its active components displayed various bioactivities such as anti-inflammation, anti-tumor, anti-oxidation, analgesic activity, antiviral and anti-microbial effects, effects on the cardiovascular system, neuroprotective function, hepatoprotective activity, effects on skin diseases and so on. Based on these studies, this review focused on the research publications of and aimed to summarize the advances in the traditional uses, phytochemistry and pharmacology which will provide reference for the further studies and applications of .
()根是一种著名的可食用药草,在中国已使用了数千年。迄今为止,已从()中发现了300多种化学成分。在这些成分中,香豆素和挥发油是主要的活性化合物。此外,还从()的根中分离出了一些其他化合物,如生物碱、酚类、甾醇、苯并呋喃、聚乙炔和多糖。现代药理学研究表明,()的根及其活性成分具有多种生物活性,如抗炎、抗肿瘤、抗氧化、镇痛、抗病毒和抗菌作用、对心血管系统的作用、神经保护功能、肝脏保护活性、对皮肤病的作用等。基于这些研究,本综述聚焦于()的研究出版物,旨在总结其传统用途、植物化学和药理学方面的进展,为()的进一步研究和应用提供参考。