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3MDR 治疗对加拿大军人和退伍军人的心理健康测量的定量变化。

Quantitative changes in mental health measures with 3MDR treatment for Canadian military members and veterans.

机构信息

Leiden University Medical Centre, Leiden University, Leiden, the Netherlands.

Alberta Health Services, Edmonton, Ottawa, Canada.

出版信息

Brain Behav. 2022 Aug;12(8):e2694. doi: 10.1002/brb3.2694. Epub 2022 Jul 18.

Abstract

OBJECTIVE

Military members and veterans are at elevated risk of treatment-resistant posttraumatic stress disorder (TR-PTSD) due to higher rates of exposure to potentially traumatic events during the course of duty. Knowledge of TR-PTSD is limited, and specific protocols or evidence-based TR-PTSD therapies are lacking. Multimodal motion-assisted memory desensitization and reconsolidation (3MDR) therapy is an emerging intervention for combat-related TR-PTSD. The purpose of this study was to preliminarily assess the effectiveness of 3MDR in addressing TR-PTSD in Canadian military members and veterans.

METHODS

This study is a longitudinal mixed-methods clinical trial. English-speaking military members and veterans aged 18-60 with TR-PTSD were recruited to participate. The intervention consisted of six sessions of 3MDR therapy. Quantitative data were collected pretreatment, posttreatment, and longitudinally at 1, 3, and 6 months after completion of 3MDR.

RESULTS

Results from the first 11 participants to complete the 3MDR protocol exhibited statistically significant improvement (surviving multiple comparison correction) in clinically administered and self-reported scores for PTSD (CAPS-5 and PCL-5), moral injury (MISS-M-SF), depression (PHQ-9), anxiety (GAD-7), emotional regulation (DERS-18), and resilience (CD-RS-25).

CONCLUSION

The preliminary and exploratory results from this clinical trial support the growing body of literature illustrating 3MDR as an effective treatment for military-related TR-PTSD. These results are notable given participants' previous lack of success with frontline psychotherapeutic and pharmacological interventions. Given that there are currently very limited treatment options for TR-PTSD, 3MDR could prove to be a valuable treatment option for military members and veterans with TR-PTSD.

摘要

目的

由于在服役期间更高的创伤后应激障碍(PTSD)暴露率,军人和退伍军人面临着治疗抵抗性 PTSD(TR-PTSD)的风险增加。对 TR-PTSD 的了解有限,缺乏特定的协议或循证治疗 TR-PTSD 的方法。多模态运动辅助记忆脱敏和再巩固(3MDR)疗法是一种新兴的针对与战斗相关的 TR-PTSD 的干预措施。本研究的目的是初步评估 3MDR 治疗加拿大军人和退伍军人 TR-PTSD 的有效性。

方法

这是一项纵向混合方法临床试验。招募了年龄在 18-60 岁之间、患有 TR-PTSD 的讲英语的军人和退伍军人参加。干预措施包括 6 次 3MDR 治疗。在治疗结束后 1、3 和 6 个月,进行了定量数据收集,同时也收集了治疗前、治疗后和纵向的数据。

结果

完成 3MDR 方案的前 11 名参与者的结果显示,在 PTSD(CAPS-5 和 PCL-5)、道德伤害(MISS-M-SF)、抑郁(PHQ-9)、焦虑(GAD-7)、情绪调节(DERS-18)和韧性(CD-RS-25)的临床评估和自我报告评分上,均有统计学意义上的显著改善(通过多次比较校正幸存)。

结论

本临床试验的初步和探索性结果支持越来越多的文献表明,3MDR 是治疗与军事相关的 TR-PTSD 的有效方法。这些结果值得注意,因为参与者之前在一线心理治疗和药物干预方面没有取得成功。鉴于目前 TR-PTSD 的治疗选择非常有限,3MDR 可能成为 TR-PTSD 的军人和退伍军人的一种有价值的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02d6/9392526/a15a04d13b6c/BRB3-12-e2694-g002.jpg

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