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使用细胞自动机方法及由此产生的平均场系统评估接触者追踪、隔离和红色区域对新冠疫情动态演变的影响:以毛里求斯为例

Assessing the Impact of Contact Tracing, Quarantine and Red Zone on the Dynamical Evolution of the Covid-19 Pandemic using the Cellular Automata Approach and the Resulting Mean Field System: A Case study in Mauritius.

作者信息

Ruhomally Yusra Bibi, Mungur Maheshsingh, Khoodaruth Abdel Anwar Hossen, Oree Vishwamitra, Dauhoo Muhammad Zaid

机构信息

Department of Mathematics, Faculty of Science, University of Mauritius, Réduit, Mauritius.

Department of Mechanical and Production Engineering, Faculty of Engineering, University of Mauritius, Réduit, Mauritius.

出版信息

Appl Math Model. 2022 Nov;111:567-589. doi: 10.1016/j.apm.2022.07.008. Epub 2022 Jul 14.

Abstract

A cellular automaton (CA) depicting the dynamics of the Covid-19 pandemic, is set up. Unlike the classic CA models, the present CA is an enhanced version, embodied with contact tracing, quarantine and red zones to model the spread of the Covid-19 pandemic. The incubation and illness periods are assimilated in the CA system. An algorithm is provided to showcase the rules governing the CA, with and without the enactment of red zones. By means of mean field approximation, a nonlinear system of delay differential equations (DDE) illustrating the dynamics of the CA is emanated. The concept of red zones is incorporated in the resulting DDE system, forming a DDE model with red zone. The stability analysis of both systems are performed and their respective reproduction numbers are derived. The effect of contact tracing and vaccination on both reproduction numbers is also investigated. Numerical simulations of both systems are conducted and real time Covid-19 data in Mauritius for the period ranged from 5 March 2021 to 2 September 2021, is employed to validate the model. Our findings reveal that a combination of both contact tracing and vaccination is indispensable to attenuate the reproductive ratio to less than 1. Effective contact tracing, quarantine and red zones have been the key strategies to contain the Covid-19 virus in Mauritius. The present study furnishes valuable perspectives to assist the health authorities in addressing the unprecedented rise of Covid-19 cases.

摘要

建立了一个描述新冠疫情动态的细胞自动机(CA)。与经典的CA模型不同,当前的CA是一个增强版本,融入了接触者追踪、隔离和红色区域来模拟新冠疫情的传播。潜伏期和发病期被纳入CA系统。提供了一种算法来展示控制CA的规则,包括有无红色区域的情况。通过平均场近似,推导出一个说明CA动态的延迟微分方程(DDE)非线性系统。红色区域的概念被纳入所得的DDE系统,形成一个带有红色区域的DDE模型。对这两个系统进行了稳定性分析,并推导了它们各自的再生数。还研究了接触者追踪和疫苗接种对两个再生数的影响。对这两个系统进行了数值模拟,并使用毛里求斯2021年3月5日至2021年9月2日期间的实时新冠数据来验证模型。我们的研究结果表明,接触者追踪和疫苗接种相结合对于将繁殖率降低到1以下是必不可少的。有效的接触者追踪、隔离和红色区域一直是毛里求斯控制新冠病毒的关键策略。本研究提供了有价值的观点,以协助卫生当局应对新冠病例前所未有的增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5323/9279002/f42701f0203b/gr2_lrg.jpg

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