Max Planck Queensland Centre on the Materials Science for Extracellular Matrices, Queensland University of Technology, Brisbane, QLD 4059, Australia.
Nat Commun. 2022 Jul 21;13(1):4222. doi: 10.1038/s41467-022-31889-x.
Despite its apparent simplicity, water behaves in a complex manner and is fundamental in controlling many physical, chemical and biological processes. The molecular mechanisms underlying interaction of water with materials, particularly polymer networks such as hydrogels, have received much attention in the research community. Despite this, a large gulf still exists in applying what is known to rationalize how the molecular organization of water on and within these materials impacts biological processes. In this perspective, we outline the importance of water in biomaterials science as a whole and give indications for future research directions towards emergence of a complete picture of water, materials and biology.
尽管水看起来很简单，但它的行为却很复杂，是控制许多物理、化学和生物过程的基础。水与材料相互作用的分子机制，特别是聚合物网络（如水凝胶），在研究界受到了广泛关注。尽管如此，在将已知知识应用于合理化水在这些材料上和内部的分子组织如何影响生物过程方面，仍然存在很大的差距。在这个观点中，我们概述了水在整个生物材料科学中的重要性，并为未来的研究方向指明了方向，以形成一幅完整的水、材料和生物学的图景。
