Wang Jianlong, Liu Bin, Hou Jiachao, Li Tao
Department of General Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Central Laboratory, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Front Surg. 2022 Jul 6;9:926003. doi: 10.3389/fsurg.2022.926003. eCollection 2022.
Undifferentiated pleomorphic sarcoma (UPS) is a malignant tumor that originates in the mesenchymal tissue and is common in the extremities and retroperitoneum. Primary UPS of the duodenal papilla is rare and a distinct clinical entity.
In this report, a 48-year-old Chinese man was admitted to our hospital with symptoms of melena. The patient underwent choledochectomy and choledochaljejunostomy for obstructive jaundice 8 years before admission. Endoscopic examination after admission confirmed a mass located at the duodenal papilla. Then, the duodenal papilla and tumor resection were performed, and the histopathology report confirmed the diagnosis of UPS. The patient refused further treatment and died 2 months later due to local recurrence and intrahepatic metastasis.
It is rare that the mass in the duodenal papilla is diagnosed as UPS. The unpredicted behavior of these tumors warrants a careful plan considering their indolent nature and possible recurrence and metastasis. The prognosis was poor despite the early complete resection.
未分化多形性肉瘤（UPS）是一种起源于间叶组织的恶性肿瘤，常见于四肢和腹膜后。十二指肠乳头原发性UPS罕见，是一种独特的临床实体。
在本报告中，一名48岁的中国男性因黑便症状入院。该患者在入院前8年因梗阻性黄疸接受了胆总管切除术和胆总管空肠吻合术。入院后内镜检查证实十二指肠乳头处有一肿块。随后，进行了十二指肠乳头和肿瘤切除术，组织病理学报告确诊为UPS。患者拒绝进一步治疗，2个月后因局部复发和肝内转移死亡。
十二指肠乳头处肿块被诊断为UPS的情况罕见。这些肿瘤不可预测的行为需要根据其惰性性质以及可能的复发和转移制定仔细的治疗计划。尽管早期进行了完整切除，预后仍较差。
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