Zhang Qi, Hou Kai, Chen Hongbo, Zeng Ning, Wu Yiping
Department of Plastic and Cosmetic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Front Oncol. 2022 Jul 7;12:933125. doi: 10.3389/fonc.2022.933125. eCollection 2022.
Recent advances in nanotechnologies for cancer diagnosis and treatment have received considerable attention worldwide. Nanoparticles are being used to create nanodrugs and probes to diagnose and treat a variety of diseases, including cancer. Nanomedicines have unique advantages, such as increased surface-to-volume ratios, which enable them to interact with, absorb, and deliver small biomolecules to a very specific target, thereby improving the effectiveness of both probes and drugs. Nanoprobe biotechnology also plays an important role in the discovery of novel cancer biomarkers, and nanoprobes have become an important part of early clinical diagnosis of cancer. Various organic and inorganic nanomaterials have been developed as biomolecular carriers for the detection of disease biomarkers. Thus, we designed this review to evaluate the advances in nanoprobe technology in tumor diagnosis.
纳米技术在癌症诊断和治疗方面的最新进展已在全球范围内受到广泛关注。纳米颗粒正被用于制造纳米药物和探针，以诊断和治疗包括癌症在内的多种疾病。纳米药物具有独特的优势，例如表面积与体积比增加，这使得它们能够与非常特定的靶点相互作用、吸收并递送小分子生物分子，从而提高探针和药物的有效性。纳米探针生物技术在新型癌症生物标志物的发现中也发挥着重要作用，纳米探针已成为癌症早期临床诊断的重要组成部分。各种有机和无机纳米材料已被开发用作检测疾病生物标志物的生物分子载体。因此，我们撰写本综述以评估纳米探针技术在肿瘤诊断方面的进展。
