Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu-42988, South Korea.
Institute of Physics - Center for Science and Education, Silesian University of Technology, Krasińskiego 8, Katowice, Poland.
Biomater Sci. 2022 Sep 13;10(18):5054-5080. doi: 10.1039/d2bm00797e.
Three-dimensional (3D) bioprinting technology has attracted a great deal of interest because it can be easily adapted to many industries and research sectors, such as biomedical, manufacturing, education, and engineering. Specifically, 3D bioprinting has provided significant advances in the medical industry, since such technology has led to significant breakthroughs in the synthesis of biomaterials, cells, and accompanying elements to produce composite living tissues. 3D bioprinting technology could lead to the immense capability of replacing damaged or injured tissues or organs with newly dispensed cell biomaterials and functional tissues. Several types of bioprinting technology and different bio-inks can be used to replicate cells and generate supporting units as complex 3D living tissues. Bioprinting techniques have undergone great advancements in the field of regenerative medicine to provide 3D printed models for numerous artificial organs and transplantable tissues. This review paper aims to provide an overview of 3D-bioprinting technologies by elucidating the current advancements, recent progress, opportunities, and applications in this field. It highlights the most recent advancements in 3D-bioprinting technology, particularly in the area of artificial organ development and cancer research. Additionally, the paper speculates on the future progress in 3D-bioprinting as a versatile foundation for several biomedical applications.
三维（3D）生物打印技术因其易于适应许多行业和研究领域，如生物医学、制造、教育和工程而引起了极大的兴趣。具体来说，3D 生物打印在医疗行业取得了重大进展，因为这项技术在生物材料、细胞和伴随元素的合成方面取得了重大突破，从而生产出复合的活体组织。3D 生物打印技术有可能实现用新分配的细胞生物材料和功能组织替代受损或受伤的组织或器官的巨大能力。几种类型的生物打印技术和不同的生物墨水可用于复制细胞并生成复杂的 3D 活体组织的支撑单元。生物打印技术在再生医学领域取得了重大进展，为许多人工器官和可移植组织提供了 3D 打印模型。本文旨在通过阐述该领域的最新进展、研究进展、机遇和应用，对 3D 生物打印技术进行概述。它强调了 3D 生物打印技术的最新进展，特别是在人工器官开发和癌症研究领域。此外，本文还推测了 3D 生物打印作为多种生物医学应用的多功能基础的未来发展。
