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[罕见肾肿瘤——甲状腺样滤泡癌]

[Rare kidney tumor - thyroid-like follicular carcinoma].

作者信息

Gappoev S V, Khorzhevskii V A, Kirichenko A K, Alymova E V, Vershinin I V, Levkovich L G

机构信息

Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia.

Krasnoyarsk State Regional Bureau of Pathology, Krasnoyarsk, Russia.

出版信息

Arkh Patol. 2022;84(4):62-70. doi: 10.17116/patol20228404162.

Abstract

The literature review provides an analysis of a rare malignant tumor of the kidney: thyroid-like follicular carcinoma of the kidney (TLFCK). In morphology, this tumor is extremely similar to thyroid follicular carcinoma, but the immunophenotype of tumor cells is different. TLFCK has an indolent clinical course, rarely metastasizes, and even the development of metastases does not mean an unfavorable prognosis for the patient. The literature review presents the features of the clinical course of the disease, macroscopic, microscopic, immunohistochemical characteristics of the tumor and typical cytogenetic breakdowns. Particular attention is paid to the issues of differential diagnosis of the tumor with other pathological processes that may microscopically resemble TLFCK.

摘要

文献综述对一种罕见的肾恶性肿瘤——肾甲状腺样滤泡癌(TLFCK)进行了分析。在形态学上,这种肿瘤与甲状腺滤泡癌极为相似,但肿瘤细胞的免疫表型有所不同。肾甲状腺样滤泡癌临床病程进展缓慢,很少发生转移,即使出现转移也并不意味着患者预后不良。文献综述介绍了该疾病的临床病程特点、肿瘤的大体、微观、免疫组化特征以及典型的细胞遗传学改变。特别关注了该肿瘤与其他可能在显微镜下与肾甲状腺样滤泡癌相似的病理过程的鉴别诊断问题。

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