Santos Adailton P, Gonçalves Lucas C, Oliveira Ana C C, Queiroz Pedro H P, Ito Célia R M, Santos Mônica O, Carneiro Lilian C
Medicine College, Federal University of Goiás, 235 Street, Goiânia 74690-900, Brazil.
Institute of Tropical Pathology and Public Health, Federal University of Goiás, 235 Street, Goiânia 74605-050, Brazil.
Antibiotics (Basel). 2022 Jul 4;11(7):894. doi: 10.3390/antibiotics11070894.
The prevalence of patients hospitalized in ICUs with COVID-19 and co-infected by pathogenic bacteria is relevant in this study, considering the integrality of treatment. This systematic review assesses the prevalence of co-infection in patients admitted to ICUs with SARS-CoV-2 infection, using the PRISMA guidelines. We examined the results of the PubMed, Embase, and SciELO databases, searching for published English literature from December 2019 to December 2021. A total of 542 rec ords were identified, but only 38 were eligible and, and of these only 10 were included. The tabulated studies represented a sample group of 1394 co-infected patients. In total, 35%/138 of the patients were co-infected with spp., 27% (17/63) were co-infected with methicillin-sensitive , 21% (84/404) were co-infected with spp., 16% (47/678) of patients were co-infected with coagulase-negative , 13% (10/80) co-infected with (ESBL), and 3% (30/1030) of patients were co-infected with . The most common co-infections were related to blood flow; although in the urinary and respiratory tracts of patients was found in 57% (12/21) of patients, coagulase negative in 44% (7/16) of patients, and was found in 37% (11/29) of patients. The present research demonstrated that co-infections caused by bacteria in patients with COVID-19 are a concern.
考虑到治疗的完整性，本研究关注了在重症监护病房（ICU）住院的新冠肺炎患者合并病原菌感染的患病率。本系统评价采用PRISMA指南，评估了入住ICU的SARS-CoV-2感染患者中合并感染的患病率。我们检索了PubMed、Embase和SciELO数据库，查找2019年12月至2021年12月发表的英文文献。共识别出542条记录，但只有38条符合条件，其中仅10条被纳入。列表研究代表了1394名合并感染患者的样本组。总体而言，35%（138/394）的患者合并感染 菌属，27%（17/63）的患者合并感染甲氧西林敏感 菌，21%（84/404）的患者合并感染 菌属，16%（47/678）的患者合并感染凝固酶阴性 菌，13%（10/80）的患者合并感染产超广谱β-内酰胺酶（ESBL）的 菌，3%（30/1030）的患者合并感染 菌。最常见的合并感染与血流有关；尽管在患者的泌尿道和呼吸道中，分别有57%（12/21）的患者检出 菌，44%（7/16）的患者检出凝固酶阴性 菌，37%（11/29）的患者检出 菌。本研究表明，新冠肺炎患者中由细菌引起的合并感染值得关注。
