State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
Ningxia Zhongning Goji Industrial and Innovative Research Institute Co., Ltd., Zhongwei 755000, China.
Molecules. 2022 Jul 11;27(14):4422. doi: 10.3390/molecules27144422.
Wolfberry ( L.) is a nutritious and medicinal fruit, and deeply processed products of wolfberry needs to be improved. In this study, nutrition, bioactive compounds, and hepaprotective activity were explored in wolfberry vinegar (WFV). The contents of nutrients including total sugar and protein in WFV samples were 2.46 and 0.27 g/100 mL, respectively. Total phenolic and flavonoid contents in WFV were 2.42 mg GAE/mL and 1.67 mg RE/mL, respectively. -Hydroxybenzoic acid and m-hydroxycinnamic acid were the main polyphenols in WFV. The antioxidant activity of WFV were 20.176 mM Trolox/L (ABTS), 8.614 mM Trolox/L (FRAP), and 26.736 mM Trolox/L (DPPH), respectively. In addition, WFV treatment effectively alleviated liver injury by improving histopathological changes and reducing liver biochemical indexes in CCl4-treated mice. WFV alleviated oxidative damage by inhibiting oxidative levels and increasing antioxidant levels. These results suggest that WFV can be utilized as a functional food to prevent oxidative liver injury.
枸杞（L.）是一种营养丰富的药用水果，需要对其深加工产品进行改进。本研究探讨了枸杞醋（WFV）中的营养成分、生物活性化合物和肝保护活性。WFV 样品中的营养成分，包括总糖和蛋白质的含量分别为 2.46 和 0.27 g/100 mL。WFV 中的总酚和类黄酮含量分别为 2.42 mg GAE/mL 和 1.67 mg RE/mL。-羟基苯甲酸和 m-羟基肉桂酸是 WFV 中的主要多酚类物质。WFV 的抗氧化活性分别为 20.176 mM Trolox/L（ABTS）、8.614 mM Trolox/L（FRAP）和 26.736 mM Trolox/L（DPPH）。此外，WFV 通过改善 CCl4 处理小鼠的组织病理学变化和降低肝生化指标，有效缓解了肝损伤。WFV 通过抑制氧化水平和提高抗氧化水平来减轻氧化损伤。这些结果表明，WFV 可用作预防氧化肝损伤的功能性食品。
