Lee Megan, Bradbury Joanne, Yoxall Jacqui, Sargeant Sally
Bond University, Gold Coast Campus, Robina, Australia.
Southern Cross University, Gold Coast Campus, Coolangatta, Australia.
Br J Nutr. 2022 Jul 27;129(8):1-8. doi: 10.1017/S0007114522002410.
Depression is a chronic and complex condition experienced by over 300 million people worldwide. While research on the impact of nutrition on chronic physical illness is well documented, there is growing interest in the role of dietary patterns for those experiencing symptoms of depression. This study aims to examine the association of diet quality (Dietary Questionnaire for Epidemiological Studies version 2) and depressive symptoms (Centre for Epidemiological Studies for Depression short form) of young Australian women over 6 years at two time points, 2003 ( 9081, Mean age = 27·6) and 2009 ( 8199, Mean age = 33·7) using secondary data from the Australian Longitudinal Study on Women's Health. A linear mixed-effects model found a small and significant inverse association of diet quality on depressive symptoms ( = -0·03, 95 % CI (-0·04, -0·02)) after adjusting for covarying factors such as BMI, social functioning, alcohol and smoking status. These findings suggest that the continuation of a healthy dietary pattern may be protective of depressive symptoms. Caution should be applied in interpreting these findings due to the small effect sizes. More longitudinal studies are needed to assess temporal relationships between dietary quality and depression.
抑郁症是一种慢性复杂疾病，全球有超过3亿人受其影响。虽然关于营养对慢性身体疾病影响的研究已有充分记录，但人们对饮食模式在抑郁症患者中的作用越来越感兴趣。本研究旨在利用澳大利亚妇女健康纵向研究的二手数据，在两个时间点（2003年，9081人，平均年龄 = 27.6岁；2009年，8199人，平均年龄 = 33.7岁），对6年间澳大利亚年轻女性的饮食质量（流行病学研究饮食问卷第2版）和抑郁症状（流行病学研究抑郁中心简表）之间的关联进行考察。一个线性混合效应模型发现，在调整了诸如体重指数、社会功能、饮酒和吸烟状况等协变量因素后，饮食质量与抑郁症状之间存在微弱但显著的负相关（β = -0.03，95%置信区间为（-0.04，-0.02））。这些发现表明，持续保持健康的饮食模式可能对抑郁症状有预防作用。由于效应量较小，在解释这些发现时应谨慎。需要更多的纵向研究来评估饮食质量与抑郁症之间的时间关系。
