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Modification of E. coli L-asparaginase with polyethylene glycol: disappearance of binding ability to anti-asparaginase serum.

作者信息

Ashihara Y, Kono T, Yamazaki S, Inada Y

出版信息

Biochem Biophys Res Commun. 1978 Jul 28;83(2):385-91. doi: 10.1016/0006-291x(78)91002-1.

DOI:10.1016/0006-291x(78)91002-1
PMID:358981
Abstract
摘要

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1
Modification of E. coli L-asparaginase with polyethylene glycol: disappearance of binding ability to anti-asparaginase serum.用聚乙二醇修饰大肠杆菌L-天冬酰胺酶：与抗天冬酰胺酶血清结合能力的丧失。
Biochem Biophys Res Commun. 1978 Jul 28;83(2):385-91. doi: 10.1016/0006-291x(78)91002-1.
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Chemical modification of L-asparaginase with a comb-shaped copolymer of polyethylene glycol derivative and maleic anhydride.用聚乙二醇衍生物与马来酸酐的梳状共聚物对L-天冬酰胺酶进行化学修饰。
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5
[Antigenic properties of 1-asparaginases isolated from different species and strains of bacteria].[从不同种类和菌株的细菌中分离出的天冬酰胺酶的抗原特性]
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Increased antitumor activity of Escherichia coli. L-asparaginase by modification with monomethoxypolyethylene glycol.通过单甲氧基聚乙二醇修饰提高大肠杆菌L-天冬酰胺酶的抗肿瘤活性。
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Chemical and immunological characteristics of four different L-asparaginase preparations.四种不同L-天冬酰胺酶制剂的化学和免疫学特性
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ACtivity stain for the detection of L-asparaginase- anti-L-asparaginase complexes in agar.用于在琼脂中检测L-天冬酰胺酶-抗L-天冬酰胺酶复合物的活性染色。
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Characterization of polyethylene glycol-modified L-asparaginase from Escherichia coli and its application to therapy of leukemia.大肠杆菌聚乙二醇修饰L-天冬酰胺酶的表征及其在白血病治疗中的应用。
Jpn J Cancer Res. 1986 Dec;77(12):1264-70.
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Pharmacology of Escherichia coli-L-asparaginase polyethylene glycol adduct.大肠杆菌-L-天冬酰胺酶聚乙二醇加合物的药理学
Anticancer Res. 1981;1(6):373-6.

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Thiol-maleimide poly(ethylene glycol) crosslinking of L-asparaginase subunits at recombinant cysteine residues introduced by mutagenesis.
通过突变引入重组半胱氨酸残基，巯基-马来酰亚胺聚乙二醇交联天冬酰胺酶亚基。
PLoS One. 2018 Jul 27;13(7):e0197643. doi: 10.1371/journal.pone.0197643. eCollection 2018.
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Enhanced stability of L-asparaginase by its bioconjugation to poly(styrene-co-maleic acid) and Ecoflex nanoparticles.通过将 L-天冬酰胺酶与聚（苯乙烯-co-马来酸）和 Ecoflex 纳米粒子进行生物偶联来提高其稳定性。
IET Nanobiotechnol. 2018 Jun;12(4):466-472. doi: 10.1049/iet-nbt.2017.0156.
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Curr Gastroenterol Rep. 2001 Feb;3(1):30-7. doi: 10.1007/s11894-001-0038-z.
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Chemical modification of natural human tumor necrosis factor-alpha with polyethylene glycol increases its anti-tumor potency.用聚乙二醇对天然人肿瘤坏死因子-α进行化学修饰可增强其抗肿瘤效力。
Jpn J Cancer Res. 1994 Jan;85(1):9-12. doi: 10.1111/j.1349-7006.1994.tb02879.x.
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Polymer conjugates. Pharmacokinetic considerations for design and development.聚合物缀合物。设计与开发中的药代动力学考量。
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Immunological properties of conjugates of ragweed pollen antigen E with methoxypolyethylene glycol or a copolymer of D-glutamic acid and D-lysine.豚草花粉抗原E与甲氧基聚乙二醇或D-谷氨酸和D-赖氨酸共聚物的缀合物的免疫学特性。
J Exp Med. 1979 Feb 1;149(2):424-35. doi: 10.1084/jem.149.2.424.