Wang P, Wang G Y, Ji S Z, Ma J M, Tang T
Department of Burns and Plastic Surgery, Linfen Central Hospital, Linfen 041000, China.
Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Burn Institute of PLA, Shanghai 200433, China.
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jul 20;38(7):697-700. doi: 10.3760/cma.j.cn501120-20210709-00242.
Chronic and infectious wound healing has always been an issue of concern in clinical and scientific research, in which bacterial infection and oxidative damage are the key factors hindering wound healing. Carbon dots, as a new material, has attracted much attention because of its unique physical and chemical properties and good biological safety. In recent years, the researches on the antibacterial property, antioxidant, and photoluminescence properties of carbon dots are more and more extensive and carbon dots have great potential in the treatment of chronic and infectious wounds. This paper reviews the research progress of carbon dots in three aspects: antibacterial, anti-oxidation and monitoring of wound infection are reviewed, and further discusses its specific mechanism, potential research direction, and application prospect.
慢性和感染性伤口愈合一直是临床和科研领域关注的问题，其中细菌感染和氧化损伤是阻碍伤口愈合的关键因素。碳点作为一种新型材料，因其独特的物理化学性质和良好的生物安全性而备受关注。近年来，关于碳点的抗菌性能、抗氧化性能和光致发光性能的研究越来越广泛，碳点在慢性和感染性伤口治疗中具有巨大潜力。本文综述了碳点在抗菌、抗氧化和伤口感染监测三个方面的研究进展，并进一步探讨了其具体作用机制、潜在研究方向和应用前景。
