Brak Ivan V, Filimonova Elena, Zakhariya Oleg, Khasanov Rustam, Stepanyan Ivan
Laboratory of Comprehensive Problems of Risk Assessment to Population and Workers' Health, Federal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health", Moscow, Russia.
"Engiwiki" Scientific and Engineering Projects Laboratory, Department of Information Technologies, Novosibirsk State University, Novosibirsk, Russia.
Front Neurosci. 2022 Jul 12;16:781488. doi: 10.3389/fnins.2022.781488. eCollection 2022.
Decrease in cognitive function is one of the most common causes of poor life quality and early disability in patients with Parkinson's disease (PD). Existing methods of treatment are aimed at both correction of motor and non-motor symptoms. Methods of adjuvant therapy (or complementary therapy) for maintaining cognitive functions in patients with PD are of interest. A promising subject of research in this regard is the method of transcranial electric current stimulation (tES). Here we reviewed the current understanding of the pathogenesis of cognitive impairment in PD and of the effects of transcranial direct current stimulation and transcranial alternating current stimulation on the cognitive function of patients with PD-MCI (Parkinson's Disease-Mild Cognitive Impairment).
认知功能下降是帕金森病（PD）患者生活质量低下和早期残疾的最常见原因之一。现有的治疗方法旨在纠正运动和非运动症状。维持PD患者认知功能的辅助治疗（或补充治疗）方法备受关注。在这方面，一个有前景的研究课题是经颅电流刺激（tES）方法。在此，我们综述了目前对PD认知障碍发病机制的理解，以及经颅直流电刺激和经颅交流电刺激对PD-轻度认知障碍（PD-MCI）患者认知功能的影响。
