Neurotechnology Center, Department of Biological Sciences, Columbia University, New York, NY, USA.
Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA.
Philos Trans R Soc Lond B Biol Sci. 2021 Mar 15;376(1820):20190763. doi: 10.1098/rstb.2019.0763. Epub 2021 Jan 25.
As one of the first model systems in biology, the basal metazoan has been revealing fundamental features of living systems since it was first discovered by Antonie van Leeuwenhoek in the early eighteenth century. While it has become well-established within cell and developmental biology, this tiny freshwater polyp is only now being re-introduced to modern neuroscience where it has already produced a curious finding: the presence of low-frequency spontaneous neural oscillations at the same frequency as those found in the default mode network in the human brain. Surprisingly, increasing evidence suggests such spontaneous electrical low-frequency oscillations (SELFOs) are found across the wide diversity of life on Earth, from bacteria to humans. This paper reviews the evidence for SELFOs in diverse phyla, beginning with the importance of their discovery in , and hypothesizes a potential role as electrical organism organizers, which supports a growing literature on the role of bioelectricity as a 'template' for developmental memory in organism regeneration. This article is part of the theme issue 'Basal cognition: conceptual tools and the view from the single cell'.
作为生物学中的第一个模式系统，基础后生动物自 18 世纪初被 Antonie van Leeuwenhoek 首次发现以来，一直揭示着生命系统的基本特征。虽然它在细胞和发育生物学中已经得到了很好的确立，但这种微小的淡水水螅现在才被重新引入现代神经科学领域，在那里它已经产生了一个有趣的发现：低频自发神经振荡的存在与人类大脑默认模式网络中的频率相同。令人惊讶的是，越来越多的证据表明，这种自发的电低频振荡（SELFOs）存在于地球上从细菌到人类的广泛生物多样性中。本文综述了不同门的 SELFOs 的证据，首先从它们在 中的发现的重要性开始，并假设了作为电生物体组织者的潜在作用，这支持了越来越多的关于生物电作为生物体再生发育记忆“模板”的文献。本文是主题为“基础认知：概念工具和单细胞视角”的一部分。
