β-羟基-β-甲基丁酸（HMB）对老年人群肌肉力量的影响：一项荟萃分析。

Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis.

作者信息

Lin Ziru, Zhao Anqi, He Jiguo

机构信息

China Agricultural University, Beijing, China.

出版信息

Front Nutr. 2022 Jul 13;9:914866. doi: 10.3389/fnut.2022.914866. eCollection 2022.

OBJECTIVE

This meta-analysis aims to evaluate the effect of the emerging nutritional ingredient β-hydroxy-β-methylbutyrate (HMB) on the muscle strength of elderly people.

METHODS

Computer systems-based search and sorting of relevant documents published before December 2020 in the China Journal Full-text Database (CNKI), Wan Fang Database (Wan Fang), VIP Chinese Science and Technology Journal Database (VIP), PubMed, Web of Science, and EMbase Database was done. Two researchers independently screened the literature based on the inclusion and exclusion criteria and performed data extraction and quality evaluation. Rev Man 5.X software was used for systematic review and meta-analysis.

RESULTS

A total of 9 randomized controlled trials (RCT) studies were included in the study, which comprised 896 subjects. The overall impact on muscle strength-related indicators (SMD = 0.41; 95% CI: 0.28, 0.54); < 0.00001) was statistically significant. Conclusion: Supplementation of HMB and preparations containing HMB ingredients aid in increasing muscle strength in the elderly population.

目的

本荟萃分析旨在评估新兴营养成分β-羟基-β-甲基丁酸酯（HMB）对老年人肌肉力量的影响。

方法

基于计算机系统检索并筛选2020年12月之前在中国知网（CNKI）、万方数据库（万方）、维普中文科技期刊数据库（维普）、PubMed、科学网和EMbase数据库中发表的相关文献。两名研究人员根据纳入和排除标准独立筛选文献，并进行数据提取和质量评估。使用Rev Man 5.X软件进行系统评价和荟萃分析。