Hong Seung Wook, Byeon Jeong-Sik
Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Intest Res. 2022 Jul;20(3):281-290. doi: 10.5217/ir.2021.00169. Epub 2022 Jul 26.
Early colorectal cancer refers to cancer in the colorectum that is confined to the mucosa or submucosa and does not invade the muscularis propria, irrespective of lymph node or distant metastasis. As the number of persons undergoing screening colonoscopy increases, the proportion of patients diagnosed with precancerous colorectal lesions and early colorectal cancer also increases. In the last decade, innovative optical technologies for endoscopic diagnosis have been introduced and endoscopic treatment techniques such as endoscopic submucosal dissection have provided major breakthroughs in the management of early colorectal cancer. With these remarkable developments, endoscopic treatment has established itself as an alternative to surgical resection in the treatment of early colorectal cancer. This review will discuss the endoscopic diagnosis and treatment of early colorectal cancer. Furthermore, the unmet needs in this field and the latest research addressing those issues will be summarized.
早期结直肠癌是指局限于结直肠黏膜或黏膜下层、未侵犯固有肌层的癌症，无论有无淋巴结转移或远处转移。随着接受筛查结肠镜检查的人数增加，被诊断为结直肠癌前病变和早期结直肠癌的患者比例也在上升。在过去十年中，用于内镜诊断的创新光学技术不断涌现，内镜黏膜下剥离术等内镜治疗技术在早期结直肠癌的治疗方面取得了重大突破。随着这些显著进展，内镜治疗已成为早期结直肠癌治疗中手术切除的替代方法。本文将讨论早期结直肠癌的内镜诊断和治疗。此外，还将总结该领域尚未满足的需求以及针对这些问题的最新研究。
